Capsaicin as an anti-obesity drug

FW Leung - Capsaicin as a therapeutic molecule, 2014 - Springer
Laboratory studies support a role of capsaicin as an anti-obesity agent. Intestinal mucosal
afferent nerves appear to play a role in controlling adipose tissue distribution between …

Capsaicinoids: a spicy solution to the management of obesity?

A Tremblay, H Arguin, S Panahi - International journal of obesity, 2016 - nature.com
Capsaicin is the molecule that is responsible for the pungency of hot peppers. It stimulates
the sympathoadrenal system that mediates the thermogenic and anorexigenic effects of …

[HTML][HTML] Effects of novel capsinoid treatment on fatness and energy metabolism in humans: possible pharmacogenetic implications

S Snitker, Y Fujishima, H Shen, S Ott… - The American journal of …, 2009 - Elsevier
Abstract Background Capsinoids from the Capsicum genus of plants are nonpungent
capsaicin-related substances with effects on metabolism and body weight in animals …

Capsaicin-sensitive intestinal mucosal afferent mechanism and body fat distribution

FW Leung - Life sciences, 2008 - Elsevier
This report summarizes clinical and experimental data in support of the hypothesis that
capsaicin-sensitive intestinal mucosal afferent mechanism plays a role in regulating body fat …

Dietary capsaicin and its anti-obesity potency: from mechanism to clinical implications

J Zheng, S Zheng, Q Feng, Q Zhang… - Bioscience reports, 2017 - portlandpress.com
Obesity is a growing public health problem, which has now been considered as a pandemic
non-communicable disease. However, the efficacy of several approaches for weight loss is …

Capsaicin and capsiate could be appropriate agents for treatment of obesity: A meta-analysis of human studies

C Zsiborás, R Mátics, P Hegyi, M Balaskó… - Critical Reviews in …, 2018 - Taylor & Francis
Consumption of capsaicin or its nonpungent analogues, capsinoids has been reported to
affect energy expenditure and fat oxidation, although available data are still controversial …

[HTML][HTML] Nonpungent capsaicin analogs (capsinoids) increase energy expenditure through the activation of brown adipose tissue in humans

T Yoneshiro, S Aita, Y Kawai, T Iwanaga… - The American journal of …, 2012 - Elsevier
Background: Capsinoids—nonpungent capsaicin analogs—are known to activate brown
adipose tissue (BAT) thermogenesis and whole-body energy expenditure (EE) in small …

Topical application of capsaicin reduces visceral adipose fat by affecting adipokine levels in high‐fat diet‐induced obese mice

GR Lee, MK Shin, DJ Yoon, AR Kim, R Yu, NH Park… - …, 2013 - Wiley Online Library
Objective: Visceral obesity contributes to the development of obesity‐related disorders such
as diabetes, hyperlipidemia, and fatty liver disease, as well as cardiovascular diseases. In …

Capsinoids, non-pungent capsaicin analogs, reduce body fat accumulation without weight rebound unlike dietary restriction in mice

S Haramizu, F Kawabata, Y Masuda… - Bioscience …, 2011 - jstage.jst.go.jp
Enhancing energy expenditure and reducing energy intake are both crucial for weight
control. Capsinoids, which are non-pungent capsaicin analogs, are known to suppress body …

Anti-obesity effects of capsaicin and the underlying mechanisms: A review

R Li, Y Lan, C Chen, Y Cao, Q Huang, CT Ho, M Lu - Food & function, 2020 - pubs.rsc.org
Obesity and overweight have become serious health problems in the world and are linked to
a variety of metabolic disorders. Phytochemicals with a weight-loss effect have been widely …