Tethering factors mediate initial interaction of transport vesicles with target membranes.
Soluble N-ethylmaleimide–sensitive fusion protein attachment protein receptors (SNAREs) …

Fusion of transport vesicles with their target organelles involves specific membrane proteins,
SNAREs, which form tight complexes bridging the membranes to be fused. Evidence from …

Most membrane fusion reactions in eukaryotic cells are mediated by multisubunit tethering
complexes (MTCs) and SNARE proteins. MTCs are much larger than SNAREs and are …

Intracellular transport is largely dependent on vesicles that bud off from one compartment
and fuse with the target compartment. The first contact of an incoming vesicle with the target …

A screen for mutants of Saccharomyces cerevisiae secretory pathway components
previously yielded sec34, a mutant that accumulates numerous vesicles and fails to …

The Exocyst is a conserved multisubunit complex involved in the docking of post-Golgi
transport vesicles to sites of membrane remodeling during cellular processes such as …

Abstract p115 tethers coat protein (COP) I vesicles to Golgi membranes. The acidic COOH-
terminal domain of p115 links the Golgins, Giantin on COPI vesicles, to GM130 on Golgi …

Vesicle Tethers Promoting Fusion Machinery Assembly: Developmental Cell Skip to Main
Content Advertisement Developmental Cell This journal offers authors two options (open access …

Membrane trafficking involves the collection of cargo into nascent transport vesicles that bud
off from a donor compartment, translocate along cytoskeletal tracks, and then dock and fuse …

Membrane fusion in cells involves the interaction of SNARE proteins on apposing
membranes. Formation of SNARE complexes is preceded by tethering events, and a …