TRPM2: a multifunctional ion channel for calcium signalling
A Sumoza‐Toledo, R Penner - The Journal of physiology, 2011 - Wiley Online Library
The transient potential receptor melastatin‐2 (TRPM2) channel has emerged as an
important Ca2+ signalling mechanism in a variety of cells, contributing to cellular functions …
important Ca2+ signalling mechanism in a variety of cells, contributing to cellular functions …
Identification of direct and indirect effectors of the transient receptor potential melastatin 2 (TRPM2) cation channel
B Tóth, L Csanády - Journal of Biological Chemistry, 2010 - ASBMB
Transient receptor potential melastatin 2 (TRPM2) is a Ca 2+-permeable cation channel
involved in physiological and pathophysiological processes linked to oxidative stress …
involved in physiological and pathophysiological processes linked to oxidative stress …
Conserved cysteine residues in the pore region are obligatory for human TRPM2 channel function
ZZ Mei, HJ Mao, LH Jiang - American Journal of Physiology …, 2006 - journals.physiology.org
TRPM2 proteins belong to the melastatin-related transient receptor potential or TRPM
subfamily and form Ca2+-permeable cationic channels activated by intracellular adenosine …
subfamily and form Ca2+-permeable cationic channels activated by intracellular adenosine …
Putative chanzyme activity of TRPM2 cation channel is unrelated to pore gating
B Tóth, I Iordanov, L Csanády - Proceedings of the National …, 2014 - National Acad Sciences
Transient receptor potential melastatin 2 (TRPM2) is a Ca2+-permeable cation channel
expressed in immune cells of phagocytic lineage, pancreatic β cells, and brain neurons and …
expressed in immune cells of phagocytic lineage, pancreatic β cells, and brain neurons and …
Critical intracellular Ca2+ dependence of transient receptor potential melastatin 2 (TRPM2) cation channel activation
TRPM2 is a member of the melastatin-related TRP (transient receptor potential) subfamily. It
is expressed in brain and lymphocytes and forms a cation channel that is activated by …
is expressed in brain and lymphocytes and forms a cation channel that is activated by …
The TRPM ion channel subfamily: molecular, biophysical and functional features
A Fleig, R Penner - Trends in pharmacological sciences, 2004 - cell.com
Significant progress in the molecular and functional characterization of a subfamily of genes
that encode melastatin-related transient receptor potential (TRPM) cation channels has …
that encode melastatin-related transient receptor potential (TRPM) cation channels has …
TRPM2 and TRPM7: channel/enzyme fusions to generate novel intracellular sensors
AM Scharenberg - Pflügers Archiv, 2005 - Springer
Within the transient receptor potential (Trp) superfamily of ion channels, three members of
the Trp (melastatin)(TRPM) subfamily stand out as their amino acid sequences indicate that …
the Trp (melastatin)(TRPM) subfamily stand out as their amino acid sequences indicate that …
Negatively charged amino acids near and in transient receptor potential (TRP) domain of TRPM4 channel are one determinant of its Ca2+ sensitivity
S Yamaguchi, A Tanimoto, K Otsuguro, H Hibino… - Journal of Biological …, 2014 - ASBMB
Transient receptor potential (TRP) channel melastatin subfamily member 4 (TRPM4) is a
broadly expressed nonselective monovalent cation channel. TRPM4 is activated by …
broadly expressed nonselective monovalent cation channel. TRPM4 is activated by …
Insights into TRPM4 function, regulation and physiological role
R Vennekens, B Nilius - Transient Receptor Potential (TRP) Channels, 2007 - Springer
In the current review we will summarise data from the recent literature describing molecular
and functional properties of TRPM4. Together with TRPM5, these channels are up till now …
and functional properties of TRPM4. Together with TRPM5, these channels are up till now …