[HTML][HTML] Identification of two α-subunit species of GTP-binding proteins, Gα15 and Gαq, expressed in rat taste buds

Y Kusakabe, E Yamaguchi, K Tanemura… - … et Biophysica Acta (BBA …, 1998 - Elsevier
We cloned cDNAs for two G protein α-subunits belonging to the Gαq family, each capable of
activating PLCβ, from rat tongue. One is a Gαq in the narrow sense, and the other, termed rat …

Comprehensive study on G protein α-subunits in taste bud cells, with special reference to the occurrence of Gαi2 as a major Gα species

Y Kusakabe, A Yasuoka, M Asano-Miyoshi… - Chemical …, 2000 - academic.oup.com
Previous studies have identified many cDNA species that encode a variety of G protein α-
subunits occurring in taste buds. These include the cDNA encoding a taste-bud-specific Gα …

GUST27 and closely related G-protein-coupled receptors are localized in taste buds together with Gi-protein α-subunit

Y Kusakabe, K Abe, K Tanemura, Y Emori… - Chemical …, 1996 - academic.oup.com
Gustatory, like olfactory signalling is probably mediated by seven-transmembrane receptors
and coupling GTP-binding proteins (G proteins). We investigated the expression of a subset …

Molecular cloning of G proteins and phosphodiesterases from rat taste cells

SK McLaughlin, PJ McKINNON, N Spickofsky… - Physiology & …, 1994 - Elsevier
To identify and characterize those proteins involved in taste transduction, we cloned G
proteins and phosphodiesterases from rat taste tissue. Using degenerate primers …

[HTML][HTML] Gβ association and effector interaction selectivities of the divergent Gγ subunit Gγ13

BL Blake, MR Wing, JY Zhou, Q Lei, JR Hillmann… - Journal of Biological …, 2001 - ASBMB
Gγ 13 is a divergent member of the Gγ subunit family considered to be a component of the
gustducin G-protein heterotrimer involved in bitter and sweet taste reception in taste bud …

[HTML][HTML] Gγ13 interacts with PDZ domain-containing proteins

Z Li, O Benard, RF Margolskee - Journal of biological chemistry, 2006 - ASBMB
The G protein γ13 subunit (Gγ13) is expressed in taste and retinal and neuronal tissues and
plays a key role in taste transduction. We identified PSD95, Veli-2, and other PDZ domain …

RGS21 is a novel regulator of G protein signalling selectively expressed in subpopulations of taste bud cells

L Von Buchholtz, A Elischer, E Tareilus… - European Journal of …, 2004 - Wiley Online Library
G‐protein‐mediated signalling processes are involved in sweet and bitter taste transduction.
In particular, the G protein α‐subunit gustducin has been implicated in these processes. One …

Functional interaction between T2R taste receptors and G-protein α subunits expressed in taste receptor cells

T Ueda, S Ugawa, H Yamamura… - Journal of …, 2003 - Soc Neuroscience
Bitter taste perception is a conserved chemical sense against the ingestion of poisonous
substances in mammals. A multigene family of G-protein-coupled receptors, T2R (so-called …

Colocalization of GPR120 with phospholipase-Cβ2 and α-gustducin in the taste bud cells in mice

S Matsumura, A Eguchi, T Mizushige, N Kitabayashi… - Neuroscience …, 2009 - Elsevier
A recent study has demonstrated that the G-protein coupled receptor GPR120 is expressed
in the taste bud cells in rats. In this study, we have identified the types of taste cell that …

Identification of novel members of G-protein coupled receptor superfamily expressed in bovine taste tissue

I Matsuoka, T Mori, J Aoki, T Sato, K Kurihara - … and biophysical research …, 1993 - Elsevier
Using reverse transcription-polymerase chain reaction (RT-PCR) and degenerate
oligonucleotide primers, we amplified novel members of two different subfamily of G-protein …