Chemosensory systems in vertebrates employ G protein–coupled receptors as sensors. In
mammals, several families of olfactory and gustatory receptors as well as specific G alpha …

The present invention provides for the first time nucleic acids encoding a taste cell Specific G-
protein coupled recep tor. These nucleic acids and the receptors that they encode are …

The Gα subunits of the G12 family of heterotrimeric G proteins, Gα12 and Gα13, are closely
related in sequences and some effectors, but they often act through different pathways or …

The invention provides a series of Gα q protein variants that functionally couple to sensory
cell receptors such as taste GPCRs (TRs) and olfactory GPCRs (ORs) in an overly …

GDNF (glial cell line‐derived neurotrophic factor) affects the survival and maintenance of
central and peripheral neurons. Using an immunocytochemical method, we examined …

Phospholipase C–type β2 (PLCβ2) is expressed in a subset of cells within mammalian taste
buds. This enzyme is involved in the transduction of sweet, bitter, and umami stimuli and …

Newly identified mammalian taste-cell-specific G protein coupled receptors, and the genes
and cDNA encoding said receptors are described. Specifically, T1R G protein-coupled …

The alpha-subunit of the trimeric G-protein complex specific for taste receptor cells of the
tongue, alpha-gustducin, is described here to be also expressed in the stomach and …

Glutamate is one candidate for the neurotransmitters and/or neuromodulators involved in
taste signaling in taste buds. Group II metabotropic glutamate receptors (mGluRs: mGluR2 …

We report the isolation of a cDNA for the α subunit of a G protein from rice (Oryza sativa L.
cv. Nipponbare). The cDNA contained an open reading frame that encoded a protein of 380 …