Differential Localization of G Proteins, G, and Go, in the Olfactory Epithelium and the Main Olfactory Bulb of the Rat

H Shinohara, K Kato, T Asano - Cells Tissues Organs, 1992 - karger.com
The immunohistochemical localization of proteins Gi1 (plus Gi3). Gi2 and Go was studied in
the olfactory epithelium and the main olfactory bulb of rats, using purified antibodies to the …

Mammalian sweet taste receptors

N Ryba, M Hoon, C Zuker, G Nelson… - US Patent App. 10 …, 2005 - Google Patents
The present invention provides isolated nucleic acid and amino acid sequences of sweet
taste receptors comprising two heterologous G-protein coupled receptor polypeptides from …

Mammalian sweet taste receptors

CS Zuker, NJP Ryba, GA Nelson, MA Hoon… - US Patent …, 2008 - Google Patents
The present invention provides isolated nucleic acid and amino acid sequences of sweet
taste receptors comprising two heterologous G-protein coupled receptor polypeptides from …

Identification of new binding partners of the chemosensory signaling protein Gγ13 expressed in taste and olfactory sensory cells

Z Liu, C Fenech, H Cadiou, S Grall, E Tili… - Frontiers in cellular …, 2012 - frontiersin.org
Tastant detection in the oral cavity involves selective receptors localized at the apical
extremity of a subset of specialized taste bud cells called taste receptor cells (TRCs). The …

T1R3 nucleic acid fragments for use thereof as probes and for generating T1R specific antibodies

JE Adler, S Zozulya, X Li, S O'connell… - US Patent …, 2012 - Google Patents
Newly identified mammalian taste-cell-specific G protein-coupled receptors, and the genes
and cDNA encoding said receptors are described. Specifically, T1R G protein-coupled …

Interaction of Gβ3s, a splice variant of the G-protein Gβ3, with Gγ-and Gα-proteins

D Rosskopf, K Koch, C Habich, J Geerdes, A Ludwig… - Cellular signalling, 2003 - Elsevier
The T-allele of a polymorphism (C825T) in the gene of the G-protein β3-subunit is
associated with a complex phenotype (hypertension, obesity, altered drug responses) and …

T2R taste receptors and genes encoding same

J Adler - US Patent App. 10/986,871, 2005 - Google Patents
Newly identified mammalian taste-cell-specific G Protein Coupled Receptors and the genes
encoding Said receptors are described. Specifically, T2R taste G Protein-Coupled …

Gγ13 colocalizes with gustducin in taste receptor cells and mediates IP3 responses to bitter denatonium

L Huang, YG Shanker, J Dubauskaite, JZ Zheng… - Nature …, 1999 - nature.com
Gustducin is a transducin-like G protein selectively expressed in taste receptor cells. The α
subunit of gustducin (α-gustducin) is critical for transduction of responses to bitter or sweet …

Promiscuous coupling of receptors to Gq class α subunits and effector proteins in pancreatic and submandibular gland cells

X Xu, JT Croy, W Zeng, L Zhao, I Davignon… - Journal of Biological …, 1998 - ASBMB
Mice with deficiencies in one or more Gq class α subunit genes were used to examine the
role of the α subunit in regulating Ca 2+ signaling in pancreatic and submandibular gland …

Characterization of a novel mammalian RGS protein that binds to Gα proteins and inhibits pheromone signaling in yeast

C Chen, B Zheng, J Han, SC Lin - Journal of Biological Chemistry, 1997 - ASBMB
Genetic studies of molecules that negatively regulate G-coupled receptor functions have led
to the identification of a large gene family with an evolutionarily conserved domain, termed …