Cytokines as therapeutic targets to reduce cardiovascular risk in chronic inflammation

AM Miller, IB McInnes - Current pharmaceutical design, 2011 - ingentaconnect.com
Patients with chronic inflammatory diseases, such as rheumatoid arthritis (RA), systemic
lupus erythematosus, psoriasis and Crohn's disease have an increased atherosclerotic risk …

[HTML][HTML] Inflammatory cytokines and atherosclerotic plaque progression. Therapeutic implications

AV Sterpetti - Current Atherosclerosis Reports, 2020 - Springer
Abstract Purpose of the Review Inflammatory cytokines play a major role in atherosclerotic
plaque progression. This review summarizes the rationale for personalized anti …

Inflammatory disorders and atherosclerosis: new therapeutic approaches.

M Charakida, F O'Neil, S Masi… - Current …, 2011 - europepmc.org
Recent evidence suggests that patients with chronic inflammatory disorders are at increased
cardiovascular risk. A number of different mechanisms have been postulated to contribute to …

Managing cardiovascular risk in patients with chronic inflammatory diseases

B Haraoui, PP Liu, KA Papp - Clinical rheumatology, 2012 - Springer
The role of traditional risk factors in the development of cardiovascular disease has been
well studied. However, the relationship between chronic inflammatory conditions and …

[HTML][HTML] Role of Inflammatory cytokines in rheumatoid arthritis and development of atherosclerosis: A review

D Bedeković, I Bošnjak, S Šarić, D Kirner, S Novak - Medicina, 2023 - mdpi.com
Uncontrolled chronic inflammation results in cardiovascular disease and early death. In this
review, we studied the impact of rheumatoid arthritis on the cardiovascular system, including …

Inflammatory cytokines in atherosclerosis: current therapeutic approaches

D Tousoulis, E Oikonomou, EK Economou… - European heart …, 2016 - academic.oup.com
The notion of atherosclerosis as a chronic inflammatory disease has intensified research on
the role of cytokines and the way these molecules act and interact to initiate and sustain …

[HTML][HTML] Anti-inflammatory therapy for cardiovascular disease

CE Kosmas, D Silverio, A Sourlas… - Annals of …, 2019 - ncbi.nlm.nih.gov
Chronic subclinical inflammation is a central process in the pathogenesis of cardiovascular
disease (CVD) and it has been linked with both the initiation and progression of …

Targeting inflammation: impact on atherothrombosis

MG Marini, C Sonnino, M Previtero… - Journal of cardiovascular …, 2014 - Springer
Atherothrombosis is a worldwide epidemic accounting for an unacceptable toll of deaths and
disabilities. Its pathophysiology is complex and hardly referable to a specific mechanism; …

Cardiovascular disease in patients with chronic inflammation: mechanisms underlying premature cardiovascular events in rheumatologic conditions

JC Mason, P Libby - European heart journal, 2015 - academic.oup.com
A variety of systemic inflammatory rheumatic diseases associate with an increased risk of
atherosclerotic events and premature cardiovascular (CV) disease. Although this recognition …

Key roles of inflammation in atherosclerosis: Mediators involved in orchestrating the inflammatory response and its resolution in the disease along with therapeutic …

YH Chan, DP Ramji - Atherosclerosis: Methods and Protocols, 2022 - Springer
Inflammation is a critical driver of all stages of atherosclerosis, from lesion development to
plaque rupture. Cytokines are mediators of the immune response and in atherosclerosis, the …