Redox homeostasis is a lifelong pursuit of cancer cells. Depending on the context, reactive
oxygen species (ROS) exert paradoxical effects on cancers; an appropriate concentration …

Reactive oxygen species (ROS) and their products are components of cell signaling
pathways and play important roles in cellular physiology and pathophysiology. Under …

The cellular REDOX regulatory systems play a central role in maintaining REDOX
homeostasis that is crucial for cell integrity, survival, and proliferation. To date, a substantial …

Cellular redox homeostasis is an essential, dynamic process that ensures the balance
between reducing and oxidizing reactions within cells and thus has implications across all …

Redox balance underlies cellular homeostasis. Cancer initiation and progression has been
linked to the disruption of redox balance and oxidative stress. Recent findings exemplify the …

Cancer cells are characterized by an increase in the rate of reactive oxygen species (ROS)
production and an altered redox environment compared to normal cells. Furthermore, redox …

Significance: For a healthy cell to turn into a cancer cell and grow out to become a tumor, it
needs to undergo a series of complex changes and acquire certain traits, summarized as …

Significance: Cancer cells that are resistant to radiation and chemotherapy are a major
problem limiting the success of cancer therapy. Aggressive cancer cells depend on elevated …

Redox regulation has been proposed to control various aspects of carcinogenesis, cancer
cell growth, metabolism, migration, invasion, metastasis and cancer vascularization. As …

Reactive oxygen species (ROS) are important pathophysiological molecules involved in vital
cellular processes. They are extremely harmful at high concentrations because they promote …