Expression profile of mRNAs from rat hippocampus and its application to microarray

T Tanaka, Y Horikawa, T Kawamoto… - Molecular brain …, 2004 - Elsevier
Stress refers to physiological or psychological stimuli that disrupt homeostasis and induce
pathophysiological conditions due to maladaptive response, sometimes resulting in mental …

Hippocampal mRNA expression profiling in mice exposed to chronic unpredictable mild stress

Y Tao, Z Xie, J Shi, R Ou, H Wu, H Shi, F Huang… - Brain Research …, 2020 - Elsevier
Depression is a state of low mood and aversion to activity, affecting a person's thoughts,
behavior, motivation, feelings and sense of well-being, which is associated with dramatical …

Dynamic effects of chronic unpredictable mild stress on the hippocampal transcriptome in rats

F Li, Y Wang, X Wang, Y Zhao… - Molecular Medicine …, 2022 - spandidos-publications.com
Stress causes extensive changes in hippocampal genomic expression, leading to changes
in hippocampal structure and function. The dynamic changes in hippocampal gene …

MicroRNA profiling and bioinformatics target analysis in dorsal hippocampus of chronically stressed rats: relevance to depression pathophysiology

M Muñoz-Llanos, MA García-Pérez, X Xu… - Frontiers in Molecular …, 2018 - frontiersin.org
Studies conducted in rodents subjected to chronic stress and some observations in humans
after psychosocial stress, have allowed to establish a link between stress and the …

Hippocampal proteomic changes of susceptibility and resilience to depression or anxiety in a rat model of chronic mild stress

M Tang, H Huang, S Li, M Zhou, Z Liu, R Huang… - Translational …, 2019 - nature.com
Chronic stressful occurrences are documented as a vital cause of both depression and
anxiety disorders. However, the stress-induced molecular mechanisms underlying the …

Gene expression profiling in the stress control brain region hypothalamic paraventricular nucleus reveals a novel gene network including amyloid beta precursor …

A Tsolakidou, L Czibere, B Pütz, D Trümbach… - BMC genomics, 2010 - Springer
Background The pivotal role of stress in the precipitation of psychiatric diseases such as
depression is generally accepted. This study aims at the identification of genes that are …

Comparative proteomic characterization of ventral hippocampus in susceptible and resilient rats subjected to chronic unpredictable stress

Y Zhang, X Zhang, N Liu, S Ren, C Xia… - Frontiers in …, 2021 - frontiersin.org
Chronic stress is an essential factor leading to depression. However, there exist individual
differences in people exposed to the same stressful stimuli. Some people display negative …

Biomarkers in the rat hippocampus and peripheral blood for an early stage of mental disorders induced by water immersion stress

K Suzuki, J Shibato, R Rakwal, M Takaura… - International Journal of …, 2023 - mdpi.com
It is difficult to evaluate the pre-symptomatic state of mental disorders and prevent its onset.
Since stress could be a trigger of mental disorders, it may be helpful to identify stress …

mRNA and microRNA profiles in the amygdala are relevant to susceptibility and resilience to psychological stress induced in mice

J Sun, Y Lu, J Yang, Z Song, W Lu, JH Wang - Journal of Molecular …, 2020 - Springer
Severe or prolonged stress increases the risk for developing psychopathological disorders.
An individual's perception of stress exposure varies greatly, as do its consequences …

cDNA microarray analysis of gene expression in the cerebral cortex and hippocampus of BALB/c mice subjected to chronic mild stress

Y Liu, N Yang, P Zuo - Cellular and molecular neurobiology, 2010 - Springer
Depressive disorders are devastating metal illness that can lead to deterioration in the social
and occupational functioning of affected individuals. The etiology and pathophysiology of …