Role of oxidative stress in Alzheimer's disease

WJ Huang, XIA Zhang, WW Chen - Biomedical reports, 2016 - spandidos-publications.com
Alzheimer's disease (AD) is the most common cause of disability in individuals aged> 65
years worldwide. AD is characterized by the abnormal deposition of amyloid β (Aβ) peptide …

Oxidative stress‐a direct bridge to central nervous system homeostatic dysfunction and Alzheimer's disease

MM Anwar - Cell biochemistry and function, 2022 - Wiley Online Library
Neurologists have highly observed a frequent increasing number of elderly patients with
Alzheimer's disease (AD) without any relevant evidence of any genetic or known AD‐linked …

Oxidative stress in Alzheimer's disease: should we keep trying antioxidant therapies?

MES Ferreira, AS de Vasconcelos… - Cellular and molecular …, 2015 - Springer
The risk of chronic diseases such as Alzheimer's disease is growing as a result of the
continuous increasing average life span of the world population, a syndrome characterized …

The role of oxidative stress in the toxicity induced by amyloid β-peptide in Alzheimer's disease

S Miranda, C Opazo, LF Larrondo, FJ Muñoz… - Progress in …, 2000 - Elsevier
One of the theories involved in the etiology of Alzheimer's disease (AD) is the oxidative
stress hypothesis. The amyloid β-peptide (Aβ), a hallmark in the pathogenesis of AD and the …

[HTML][HTML] Oxidative stress and the amyloid beta peptide in Alzheimer's disease

C Cheignon, M Tomas, D Bonnefont-Rousselot… - Redox biology, 2018 - Elsevier
Oxidative stress is known to play an important role in the pathogenesis of a number of
diseases. In particular, it is linked to the etiology of Alzheimer's disease (AD), an age-related …

Oxidative stress: A target to treat Alzheimer's disease and stroke

S Briyal, AK Ranjan, A Gulati - Neurochemistry International, 2023 - Elsevier
Oxidative stress has been established as a well-known pathological condition in several
neurovascular diseases. It starts with increased production of highly oxidizing free-radicals …

Oxidative stress in Alzheimer's disease: molecular hallmarks of underlying vulnerability

MS Uddin, MT Kabir - Biological, Diagnostic and Therapeutic Advances in …, 2019 - Springer
Alzheimer's disease (AD) is the most common neurodegenerative disease characterized by
the presence of senile plaques (SPs) and neurofibrillary tangles (NFTs) in the hippocampus …

Oxidative stress in Alzheimer's disease: implications for prevention and therapy

C Behl - Alzheimer's Disease: Cellular and Molecular Aspects of …, 2005 - Springer
Oxidative stress is a marker of neurodegeneration and has been recently shown to be also
involved in the early stages of the pathogenesis of various neurodegenerative disorders. In …

Oxidative stress hypothesis in Alzheimer's disease

WR Markesbery - Free radical biology and medicine, 1997 - Elsevier
The major hurdle in understanding Alzheimer's disease (AD) is a lack of knowledge about
the etiology and pathogenesis of selective neuron death. In recent years, considerable data …

Alzheimer disease and the role of free radicals in the pathogenesis of the disease

G Perry, PI Moreira, MS Santos… - CNS & Neurological …, 2008 - ingentaconnect.com
Oxidative stress occurs early in the progression of Alzheimer disease, significantly before
the development of the pathologic hallmarks, neurofibrillary tangles and senile plaques. All …