In pain control after laparoscopic cholecystectomy, subhepatic administration of bupivacaine
immediately after the creation of pneumoperitoneum has been shown to be more effective …

Background Although laparoscopic cholecystectomy (LC) results in less pain then open
cholecystectomy, it is not a pain-free procedure. The aim of this study was to test a new …

Background This study aimed to evaluate the optimal timing of preemptive analgesia with
bupivacaine peritoneal instillation in a prospective, randomized, double-blind, placebo …

Abstract Background and Aim: Postoperative pain is an important surgical problem. Recent
studies in pain pathophysiology have led to the hypothesis that with pre-operative …

Background: Laparoscopic cholecystectomy is characterized by a short hospital stay. Hence,
pain control on the day of surgery is increasingly important. The aim of this study was to …

SummaryBackground and objective: Intraperitoneal administration of a local anaesthetic in
combination with an opioid, for the relief of postoperative pain, has already been reported …

The analgesic effect of intraperitoneal infusion of local anesthesia after laparoscopic
cholecystectomy is controversial, and the reported results range from considerable pain …

Background A controversy exists over the effectiveness and clinical value of preemptive
analgesia. Additional studies are needed to define the optimum intensity, duration, and …

Background The effects of intraperitoneal administration of bupivacaine on pain after
laparoscopic cholecystectomy were studied in a prospective, double‐blind, randomised trial …

Objective The aim of this study was to compare the postoperative analgesic efficacy of
preincisional and intraperitoneal levobupivacaine or normal saline in patients undergoing …