Alzheimer's disease (AD) is a neurodegenerative disease characterized by cognitive decline
that afflicts as many as 45% of individuals who survive past the age of 85. AD has been …

Vascular insults can initiate a cascade of molecular events leading to neurodegeneration,
cognitive impairment, and dementia. Here, we review the cellular and molecular …

In contrast to traditional neuroncentric views of Alzheimer's disease (AD), recent findings
indicate that neurovascular dysfunction contributes to cognitive decline and …

Alzheimer's disease (AD) is the most common cause of dementia and is characterized by
progressive neurodegeneration and cognitive decline. Understanding the pathophysiology …

Alzheimer's disease (AD) is a progressive neurodegenerative disorder and the predominant
form of dementia. Since its initial description by Alois Alzheimer in 1906, several advances …

While prevailing evidence supports that the amyloid cascade hypothesis is a key component
of Alzheimer's disease (AD) pathology, many recent studies indicate that the vascular …

Aging plays an important role in the etiology of the most common age-related diseases
(ARDs), including Alzheimer's disease (AD). The increasing number of AD patients and the …

The evidence that neurovascular dysfunction is an integral part of Alzheimer's disease (AD)
pathogenesis has continued to emerge in the last decade. Changes in the brain vasculature …

The fundamental pathology in Alzheimer's disease (AD) is neuronal dysfunction leading to
cognitive impairment. The amyloid-β peptide (Aβ), derived from amyloid precursor protein, is …

Neurovascular dysfunction is an integral part of Alzheimer disease (AD). Changes in the
brain vascular system may contribute in a significant way to the onset and progression of …