Deciphering the molecular pathways of saroglitazar: A dual PPAR α/γ agonist for managing metabolic NAFLD
D Ezhilarasan - Metabolism, 2024 - Elsevier
Saroglitazar (SARO), a dual peroxisome proliferator activated receptor (PPAR)-α/γ agonist,
has been used to treat metabolic diseases such as insulin resistance and diabetic …
has been used to treat metabolic diseases such as insulin resistance and diabetic …
[HTML][HTML] The PPAR α/γ agonist saroglitazar improves insulin resistance and steatohepatitis in a diet induced animal model of nonalcoholic fatty liver disease
DP Kumar, R Caffrey, J Marioneaux, PK Santhekadur… - Scientific reports, 2020 - nature.com
Insulin resistance and hepatic lipid accumulation constitute the metabolic underpinning of
nonalcoholic steatohepatitis (NASH). We tested the hypothesis that saroglitazar, a PPAR α/γ …
nonalcoholic steatohepatitis (NASH). We tested the hypothesis that saroglitazar, a PPAR α/γ …
Saroglitazar, a PPAR‐α/γ Agonist, for Treatment of NAFLD: A randomized controlled double‐blind phase 2 Trial
S Gawrieh, M Noureddin, N Loo, R Mohseni… - …, 2021 - Wiley Online Library
Background and Aims NAFLD is characterized by insulin resistance and dysregulated lipid
and glucose metabolism. Saroglitazar, a dual peroxisome proliferator activated receptor‐α/γ …
and glucose metabolism. Saroglitazar, a dual peroxisome proliferator activated receptor‐α/γ …
New peroxisome proliferator-activated receptor agonists: potential treatments for atherogenic dyslipidemia and non-alcoholic fatty liver disease
A Sahebkar, GT Chew, GF Watts - Expert opinion on …, 2014 - Taylor & Francis
Introduction: Novel peroxisome proliferator-activated receptor (PPAR) modulators (selective
PPAR modulators [SPPARMs]) and dual PPAR agonists may have an important role in the …
PPAR modulators [SPPARMs]) and dual PPAR agonists may have an important role in the …
Saroglitazar, a dual PPAR α/γ agonist, improves atherogenic dyslipidemia in patients with non-cirrhotic nonalcoholic fatty liver disease: a pooled analysis
MS Siddiqui, D Parmar, F Sheikh, SK Sarin… - Clinical …, 2023 - Elsevier
Background & Aims Cardiovascular disease is the leading cause of mortality in nonalcoholic
fatty liver disease (NAFLD). The aim of this study was to evaluate the effects of saroglitazar …
fatty liver disease (NAFLD). The aim of this study was to evaluate the effects of saroglitazar …
[HTML][HTML] Saroglitazar in patients with non-alcoholic fatty liver disease and diabetic dyslipidemia: a prospective, observational, real world study
Saroglitazar, a dual peroxisome proliferator activated receptor α/γ agonist, approved for
diabetic dyslipidemia (DD), is potential therapeutic option for non-alcoholic fatty liver …
diabetic dyslipidemia (DD), is potential therapeutic option for non-alcoholic fatty liver …
Effectiveness of The PPAR Agonist Saroglitazar in Nonalcoholic Steatohepatitis: Positive Data from Preclinical & Clinical Studies
M Krishnappa, K Patil, S Sharma, P Jain, P Trivedi… - 2020 - researchsquare.com
Background & Aims: Saroglitazar, a novel peroxisome proliferator-activated receptor (PPAR)
α/γ agonist, was evaluated in preclinical and clinical studies to evaluate its effectiveness in …
α/γ agonist, was evaluated in preclinical and clinical studies to evaluate its effectiveness in …
[HTML][HTML] Kim HH Liss
B Finck - Biochimie - bioseek.eu
Nonalcoholic fatty liver disease (NAFLD) encompasses a range of liver pathology ranging
from simple steatosis to varying degrees of inflammation, hepatocyte injury and fibrosis …
from simple steatosis to varying degrees of inflammation, hepatocyte injury and fibrosis …
[PDF][PDF] Saroglitazar in Non-alcoholic Fatty Liver Disease From Bench to Bedside: A Comprehensive Review and Sub-group Meta-Analysis
Non-alcoholic fatty liver disease (NAFLD) has become one of the most common causes of
liver diseases globally, with a projected exponential rise. In contrast to the exponential rise …
liver diseases globally, with a projected exponential rise. In contrast to the exponential rise …
Efficacy and safety of saroglitazar in real‐world patients of non‐alcoholic fatty liver disease with or without diabetes including compensated cirrhosis: A tertiary care …
S Chaudhuri, A Dutta, SBD Chakraborty - JGH Open, 2023 - Wiley Online Library
Abstract Background and Aim Saroglitazar, a dual PPAR α/γ agonist, is useful in
management of NAFLD and diabetic dyslipidemia. Here, we report the safety and efficacy of …
management of NAFLD and diabetic dyslipidemia. Here, we report the safety and efficacy of …