The progenitor and effector cell phenotype of lymphokine-activated killer (LAK) cells
generated in F344 rats by recombinant human interleukin 2 (IL-2)(rIL-2) were analyzed …

The coculture of lymphoid cells from Fischer 344 rats with recombinant human interleukin 2
(rIL-2) resulted in the generation of lymphokine-activated killer (LAK) cells. Maximal LAK …

The coculture of rat bone marrow cells with recombinant interleukin-2 induced the
generation of cells mediating natural killer (NK) activity and subsequent lymphokine …

Lymphokine-activated killer (LAK) activity has been proposed to functionally differ from
natural killer (NK) activity largely on the basis of a broader target cell spectrum and different …

A simple method for the purification and rapid expansion of large granular lymphocytes into
cells with efficient broad antitumor cytotoxicity after stimulation by human rIL-2 is described …

A highly purified population of effector lymphokine-activated killer (LAK) cells was generated
by culturing nylon-wool column nonadherent rat splenocytes in the presence of interleukin 2 …

Lymphokine-activated killer (LAK) cells can lyse a number of tumor target cells regardless of
whether the tumors are natural killer (NK) sensitive or resistant. LAK can also lyse …

The developmental relationships among large agranular lymphocytes (LAL) large granular
lymphocytes (LGL) and the activation of these cells into lymphokine-activated killer (LAK) …

Lymphokine‐activated killer (LAK) cells have been defined as interleukin 2 (lL‐2)‐activated
cytolytic effector cells exhibiting non‐MHC restricted killing against a wide range of NK …

CharaderJstics of effector cells and their progenitors in blood and spleen teukocytes in
blood and spleen can be activated by interleukin 2 (IL-2) to become cytotoxic to certain …