Dietary phytochemicals and cancer chemoprevention: a perspective on oxidative stress, inflammation, and epigenetics

W Li, Y Guo, C Zhang, R Wu, AY Yang… - Chemical research in …, 2016 - ACS Publications
Oxidative stress occurs when cellular reactive oxygen species levels exceed the self-
antioxidant capacity of the body. Oxidative stress induces many pathological changes …

A perspective on dietary phytochemicals and cancer chemoprevention: oxidative stress, nrf2, and epigenomics

ZY Su, L Shu, TO Khor, JH Lee, F Fuentes… - Natural products in …, 2013 - Springer
Oxidative stress is caused by an imbalance of reactive oxygen species (ROS)/reactive
nitrogen species (RNS) and the antioxidative stress defense systems in cells. ROS/RNS or …

[HTML][HTML] Redox-Sensitive Transcription Factors as Prime Targets for Chemoprevention with Anti-Inflammatory and Antioxidative Phytochemicals–

YJ Surh, JK Kundu, HK Na, JS Lee - The Journal of nutrition, 2005 - Elsevier
Oxidative stress has been implicated in various pathological conditions including cancer.
However, the human body has an intrinsic ability to fight against oxidative stress. A wide …

[HTML][HTML] Cancer chemoprevention by traditional chinese herbal medicine and dietary phytochemicals: targeting nrf2-mediated oxidative stress/anti-inflammatory …

JH Lee, L Shu, F Fuentes, ZY Su, ANT Kong - Journal of traditional and …, 2013 - Elsevier
Excessive oxidative stress induced by reactive oxygen species (ROS), reactive nitrogen
species (RNS), and reactive metabolites of carcinogens alters cellular homeostasis, leading …

Molecular basis of chemoprevention with dietary phytochemicals: redox-regulated transcription factors as relevant targets

JK Kundu, YJ Surh - Phytochemistry reviews, 2009 - Springer
A precise regulation of redox balance is required for the cellular homeostatic control.
Aberrant activation of redox-sensitive transcription factors, such as nuclear factor-kappaB …

Molecular pathways for cancer chemoprevention by dietary phytochemicals

AC Tan, I Konczak, DMY Sze, I Ramzan - Nutrition and cancer, 2011 - Taylor & Francis
Interest in dietary phytochemicals for potential cancer chemoprevention has increased
substantially. Screening dietary compounds for chemopreventive activity however, requires …

Dietary phytochemicals as epigenetic modifiers in cancer: Promise and challenges

E Shankar, R Kanwal, M Candamo, S Gupta - Seminars in cancer biology, 2016 - Elsevier
The influence of diet and environment on human health has been known since ages. Plant-
derived natural bioactive compounds (phytochemicals) have acquired an important role in …

Dietary phytochemicals and cancer prevention: Nrf2 signaling, epigenetics, and cell death mechanisms in blocking cancer initiation and progression

JH Lee, TO Khor, L Shu, ZY Su, F Fuentes… - Pharmacology & …, 2013 - Elsevier
Reactive metabolites from carcinogens and oxidative stress can drive genetic mutations,
genomic instability, neoplastic transformation, and ultimately carcinogenesis. Numerous …

Simultaneous activation of Nrf2 and elevation of dietary and endogenous antioxidant chemicals for cancer prevention in humans

KN Prasad - Journal of the American College of Nutrition, 2016 - Taylor & Francis
Despite extensive studies in cancer prevention, the incidence of cancer is increasing. We
review studies that have identified several biochemical and genetic defects as well as …

Nrf2–ARE signaling pathway and natural products for cancer chemoprevention

CR Zhao, XJ Qu - Cancer epidemiology, 2010 - Elsevier
BACKGROUND: One of the potential strategies for preventing cancers is using food-based
natural products to induce cytoprotective enzymes including phase II and antioxidative …