Despite rutin, extracted from black mulberry, has several pharmacological activities, its exact
effect against hepatic fibrosis remains incompletely identified. Accordingly, this study …

Rutin is a flavonol glycoside widely existing in plants, used as food antioxidant and
nutritional enhancer. Rutin has vitamin P-like effect and anti-inflammatory effect. This study …

Objective To investigate the antifibrotic role of rosmarinic acid (RA), a natural polyphenolic
compound, on HSCs activation/proliferation and apoptosis in vitro and in vivo. Methods The …

Hepatic stellate cells (HSC) play a central role in hepatic fibrosis and compounds that
promote apoptosis in HSC may have anti-fibrotic potentials. Herbal medicine has long been …

Abstract Background and Aim: There is currently no safe and effective treatment for liver
fibrosis. We have previously shown that Stephania tetrandra (ST) and Salvia miltiorrhiza …

Since the activated hepatic stellate cell (HSC) is the predominant event in the progression of
liver fibrosis, selective clearance of HSC should be a potential strategy in therapy. Salvia …

Various therapeutic approaches are conducted for regression of liver fibrosis and prevent
possible further carcinogenic transformation. This study was aimed to assess the …

Hepatic fibrosis is a wound-healing process caused by prolonged liver damage and often
occurs due to hepatic stellate cell activation in response to reactive oxygen species (ROS) …

Our study aimed to explore effects of a characterized ethanol extract of Rosa rugosa (ERS)
on hepatic stellate cells (HSCs) activation and mouse liver fibrosis and their molecular …

Abstract Background & Aims Luteolin has been reported to exert antifibrogenic effects in CC
l4‐induced hepatic fibrosis in mice. However, limited information is available on the cellular …