Circulating tRNA fragments as a novel biomarker class to distinguish acute stroke subtypes

TTM Nguyen, ML van der Bent, MJH Wermer… - International Journal of …, 2020 - mdpi.com
Early blood biomarkers to diagnose acute stroke could drastically reduce treatment delays.
We investigated whether circulating small non-coding RNAs can serve as biomarkers to …

RNA-Seq identifies circulating miR-125a-5p, miR-125b-5p, and miR-143-3p as potential biomarkers for acute ischemic stroke

S Tiedt, M Prestel, R Malik, N Schieferdecker… - Circulation …, 2017 - Am Heart Assoc
Rationale: Currently, there are no blood-based biomarkers with clinical utility for acute
ischemic stroke (IS). MicroRNAs show promise as disease markers because of their cell type …

Circulating microRNAs as novel potential biomarkers for early diagnosis of acute stroke in humans

W Wang, G Sun, L Zhang, L Shi, Y Zeng - Journal of stroke and …, 2014 - Elsevier
Background Many diseases include microRNAs (miRNAs) as reported biomarkers. The
significance of circulating miRNAs for early diagnosis of acute stroke in humans is unknown …

[HTML][HTML] Diagnostic and prognostic circulating microrna in acute stroke: a systematic and bioinformatic analysis of current evidence

J Bejleri, E Jirström, P Donovan, DJ Williams… - Journal of …, 2021 - synapse.koreamed.org
Background and Purpose Stroke is the second leading cause of death and disability
worldwide and its diagnosis, and assessment of prognosis, remains challenging. There is a …

Differential long noncoding RNA expressions in peripheral blood mononuclear cells for detection of acute ischemic stroke

QW Deng, S Li, H Wang, HL Sun, L Zuo, ZT Gu… - Clinical …, 2018 - portlandpress.com
Long noncoding RNAs (lncRNAs) have been highlighted to be involved in the pathological
process of ischemic stroke (IS). The purpose of the present study was to investigate the …

[HTML][HTML] Increased plasma levels of miR-124-3p, miR-125b-5p and miR-192-5p are associated with outcomes in acute ischaemic stroke patients receiving …

XW He, YH Shi, YS Liu, GF Li, R Zhao, Y Hu, CC Lin… - Atherosclerosis, 2019 - Elsevier
Background and aims Circulating microRNAs (miRNAs) have recently emerged as
promising biomarkers for acute ischaemic stroke (AIS). However, the expression profiles of …

Circulating microRNA profiling identifies distinct microRNA signatures in acute ischemic stroke and transient ischemic attack patients

SM Toor, EK Aldous, A Parray, N Akhtar… - International Journal of …, 2022 - mdpi.com
Transient ischemic attack (TIA) refers to a momentary neurologic deficit caused by focal
cerebral, spinal or retinal ischemic insult. TIA is associated with a high risk of impending …

Identification of novel circulating miRNAs in patients with acute ischemic stroke

EK Aldous, SM Toor, A Parray, Y Al-Sarraj… - International Journal Of …, 2022 - mdpi.com
Ischemic strokes are associated with significant morbidity and mortality, but currently there
are no reliable prognostic or diagnostic blood biomarkers. MicroRNAs (miRNAs) regulate …

Circulating microRNAs as biomarkers for acute ischemic stroke: a systematic review

B Dewdney, A Trollope, J Moxon… - Journal of Stroke and …, 2018 - Elsevier
Background Acute ischemic stroke is a leading cause of death and disability worldwide.
Unlike myocardial infarction, there is no current blood test to diagnose acute ischemic …

Circulating non-coding RNAs as potential biomarkers for ischemic stroke: a systematic review

J Zhao, Q Wang, R Zhu, J Yang - Journal of Molecular Neuroscience, 2022 - Springer
Background Recent studies have demonstrated that dysregulated non-coding RNAs
(ncRNAs) are involved in the pathogenesis of ischemic stroke (IS), including …