Low serum levels of high-density lipoprotein cholesterol (HDL-C) are highly prevalent and
are recognized as an independent risk factor for cardiovascular morbidity (myocardial …

There is evidence to support the view that HDL functionality and the mechanism by which a
therapeutic agent raises HDL-C are more important than plasma HDL-C levels. Future …

Plasma concentrations of HDL cholesterol are inversely correlated with risk of coronary
heart disease, and low HDL-cholesterol levels are a risk factor even in patients aggressively …

Background High-density lipoprotein (HDL) is believed to have atheroprotective properties,
but an effective HDL-based therapy remains elusive. Early studies have suggested that …

Objectives: This study aimed to determine whether serial autologous infusions of selective
high-density lipoprotein (HDL) delipidated plasma are feasible and well tolerated in patients …

Low-density lipoproteins (LDL) are considered as important risk factors for cardiovascular
diseases (CVD), while highdensity lipoproteins (HDL) are well recognized for their putative …

This review aims to provide an overview on the properties of high‐density lipoproteins
(HDLs) and their cardioprotective effects. Emergent HDL therapies will be presented in the …

There is robust epidemiological evidence dating back to the original Framingham Heart
Study from 1977 that indicates an important inverse relationship between high-density …

Cardiovascular disease (CVD) remains a major burden for morbidity and mortality in the
general population, despite current efficacious low-density lipoprotein-cholesterol–lowering …

FOR MORE THAN 3DECADES, SINCE HIGH LEVELS OF HIGH-density lipoprotein
cholesterol (HDL-C) were first linked to a lower risk of developing cardiovascular disease …