Myeloid cells, including monocytes and macrophages participate in steady state immune
homeostasis and help mount the adaptive immune response during infection. The function …

Inflammation and immune processes underlie pulmonary hypertension progression. Two
main different activated phenotypes of macrophages, classically activated M1 macrophages …

Pulmonary hypertension (PH) is a pathophysiological disorder that can complicate most
cardiovascular and respiratory diseases and may involve multiple clinical conditions, but its …

Pulmonary inflammation, which is characterized by the presence of perivascular
macrophages, has been proposed as a key pathogenic driver of pulmonary hypertension …

Pulmonary hypertension (PH) is a life-threatening pathological state with elevated
pulmonary arterial pressure, resulting in right ventricular failure and heart functional failure …

Pulmonary arterial hypertension (PAH) is a progressive disease characterized by
remodeling of the pulmonary arteries, increased pulmonary infiltrates, loss of vascular cross …

Pulmonary hypertension (PH) represents a grave condition associated with high morbidity
and mortality, emphasizing a desperate need for innovative and targeted therapeutic …

Pulmonary arterial hypertension (PAH) is a severe cardiopulmonary vascular disease
characterized by progressive pulmonary artery pressure elevation, increased pulmonary …

The recruitment and subsequent polarization of inflammatory monocytes/macrophages in
the perivascular regions of pulmonary arteries is a key feature of pulmonary hypertension …

In severe pulmonary arterial hypertension (PAH), vascular lesions are composed of
phenotypically altered vascular and inflammatory cells that form clusters or tumorlets …