Methamphetamine is a highly abused psychostimulant that substantially impacts public
health. Prenatal and postnatal methamphetamine exposure alters gene expression, brain …

The effects of early life stress in utero or in neonates has long-term consequences on
hypothalamic-pituitary-adrenal (HPA) stress axis function and neurodevelopment. These …

The rise in rates of opioid abuse in recent years in the United States has led to a dramatic
increase in the incidence of neonatal abstinence syndrome (NAS). Despite improved …

Early gestation is a neurodevelopmental period that is especially vulnerable to
environmental insult and one in which neurogenesis features prominently. Prenatal …

Prenatal stress has been associated with detrimental outcomes of pregnancy, including
altered brain development leading to behavioural pathologies. The neurosteroid …

Recently, both glucocorticoid receptor immunoreactivity and glucocorticoid receptor
messenger RNA levels were found in multiple brain areas, especially in the neuroepithelium …

The noradrenergic system plays an important role in prefrontal cortex (PFC) function. Since
early life experiences play a crucial role in programming brain function, we investigated the …

In this study, we assessed behavioral responses to social separation at 8 months of age and
cerebrospinal fluid (CSF) concentrations of biogenic amines and metabolites at 8 and 18 …

While many experiment with drugs, relatively few individuals develop a true addiction. We
hypothesized that, in rats, such individual differences in the actions of addictive drugs might …

Continuous exposure of non-parturient rats to pups can induce maternal behavior similar in
most aspects to that found in the postpartum rat. Surprisingly, young juvenile rats (20–24 …