Rationale Obstetric complications involving birth hypoxia are implicated in the etiology of
disorders with dopaminergic dysfunction, such as schizophrenia. Cesarean section (C …

The prefrontal cortex (PFC) undergoes dramatic, sex‐specific maturation during
adolescence. Adolescence is a vulnerable window for developing mental illnesses that …

Dopaminergic signaling and neurodevelopment alterations are associated with several
neuropsychiatric disorders. Knockout mice for dopamine transporters (DAT) as well as site …

Clinical studies have suggested that early-life stress (ELS) increases the risk of
psychopathologies that are strongly associated with dysfunction of dopaminergic …

The timeline of dopamine (DA) system maturation and the signaling properties of DA
receptors (DRs) during rat brain development are not fully characterized. We used in situ …

The early appearance of monoamine systems in the developing mammalian CNS suggests
that they play a role in neural development. We review data from two model systems that …

Maturation of the nervous system and consequent behavior depends in part on prenatal
nutritional factors and postnatal environmental stimulation. In particular, the hypothalamus …

Central dopaminergic (DA) systems appear to be particularly vulnerable to disruption by
exposure to stressors in early life, but the underlying mechanisms are poorly understood. As …

Dopamine in the prefrontal cortex plays a critical role in normal cognition throughout the
lifespan and has been implicated in the pathophysiology of neuropsychiatric disorders such …

Quantitative in vitro autoradiography was used to study the postnatal development of
monoaminergic receptors (D1 and D2 dopaminergic, 5-HT1 and 5-HT2 serotonergic, and …