This study examined the striatal dopamine system integrity and associated behavior in 5-to 7-
year-old rhesus monkeys born from mothers that experienced stress and/or consumed …

We have previously reported that an apparently uncomplicated Caesarean section birth
produces long-term alterations in steady-state levels of dopamine in the central nervous …

Background: Preterm birth is a major cause of neurodevelopmental disorders.
Allopregnanolone, a key metabolite of progesterone, has neuroprotective and …

The goal of this research was to examine the effect of preconception paternal stress (PPS)
on the subsequent neurodevelopment and behavior of male and female offspring. Prenatal …

Cocaine exposure in utero is known to cause a variety of behavioral and motor deficits that
may be attributable to alterations in the dopamine neurocircuitry. To ascertain cocaine …

The dopamine (DA) receptor antagonist, haloperidol (HAL, 1.25 or 5 mg/kg), or vehicle,
dimethyl sulfoxide (DMSO), was administered (SC) daily to pregnant SpragueDawley dams …

Rationale The birth of neurons, their migration to appropriate positions in the brain, and their
establishment of the proper synaptic contacts happen predominately during the prenatal …

Amphetamines are among the most widely abused drugs. The user population includes a
large proportion of women of child-bearing age. The early ontogeny of the axons in the …

Progesterone and its neuroactive metabolite, allopregnanolone, are present in high
concentrations during pregnancy, but drop significantly following birth. Allopregnanolone …

During critical or sensitive periods of development, the brain is highly plastic and particularly
vulnerable to environmental adverse effects, including stress. In response to gestational …