Damage to the peripheral nervous system often leads to chronic neuropathic pain
characterized by spontaneous pain and an exaggerated response to painful and/or …

2. Methods This is a narrative review based on the authors' research and on that of groups
working in the same area. Given the vast amount of data in the field, it is not possible to …

Damage to peripheral nerves often results in pain and hyperalgesia. We suggest that nerve
damage causes an inflammatory response in which cells associated with the nerve release …

A high-intensity potentially tissue-injuring stimulus generates a homotopic response to
escape the stimulus and is associated with an affective phenotype considered to represent …

Evidence indicates that central glial activation depends on nerve inputs from the site of injury
and release of chemical mediators. Hematogenous immune cells may migrate to/infiltrate …

A review of central neuropathic pain states : Current Opinion in Anesthesiology A review of
central neuropathic pain states : Current Opinion in Anesthesiology Log in or Register …

One area that has emerged as a promising therapeutic target for the treatment and
prevention of chronic pain and opioid tolerance/hyperalgesia is the modulation of the central …

Pain is a major symptom of many different diseases. Modern pain research has uncovered
important neuronal mechanisms that are underlying clinically relevant pain states, and …

Clinical characteristics of neuropathic pain, ie pain after nervous system lesions, are burning
spontaneous pain, shooting pain attacks and evoked pains. Partly interacting …

Neuropathic pain (NP) is a significant and disabling clinical problem with very few
therapeutic treatment options available. A major priority is to identify the molecular …