Adult haematopoietic stem cells (HSCs) mainly reside in the bone marrow, where stromal
and haematopoietic cells regulate their function. The steady state HSC niche has been …

The bone marrow (BM) microenvironment, also called the BM niche, is essential for the
maintenance of fully functional blood cell formation (hematopoiesis) throughout life. Under …

Self-renewing hematopoietic stem cells and their progeny, lineage-specific downstream
progenitors, maintain steady-state hematopoiesis in the bone marrow (BM). Accumulating …

The bone marrow microenvironment contains a heterogeneous population of stromal cells
organized into niches that support hematopoietic stem cells (HSCs) and other lineage …

Hematopoietic stem cells (HSC) reside in the bone marrow (BM) within a specialized micro-
environment, the HSC niche, which comprises several cellular constituents. These include …

The haematopoietic stem cell (HSC) microenvironment in the bone marrow, termed the
niche, ensures haematopoietic homeostasis by controlling the proliferation, self-renewal …

Hematopoietic stem cell (HSC) behavior is governed in large part by interactions of the
blood system with the bone microenvironment. Increasing evidence demonstrates the …

Hematopoietic stem cells (HSCs) possess the ability to self-renew and to differentiate to
mature progeny along multiple different hematopoietic lineages. The function of HSCs …

The skeleton serves as the principal site for hematopoiesis in adult terrestrial vertebrates.
The function of the hematopoietic system is to maintain homeostatic levels of all circulating …

ARTICLE SERIES: Stem Cells Cell Science at a Glance 3529 dormancy (Trumpp et al.,
2010) and, thereby, maintain homeostasis both in the steady state as well as in response to …