Prevention and treatment of Staphylococcus aureus biofilms

M Bhattacharya, DJ Wozniak, P Stoodley… - Expert review of anti …, 2015 - Taylor & Francis
S. aureus colonizes both artificial and tissue surfaces in humans causing chronic persistent
infections that are difficult to cure. It is a notorious pathogen due to its antibiotic recalcitrance …

An update on recent developments in the prevention and treatment of Staphylococcus aureus biofilms

MK Suresh, R Biswas, L Biswas - International Journal of Medical …, 2019 - Elsevier
Staphylococcus aureus (S. aureus) readily forms biofilms on prosthetic devices such as the
pacemakers, heart valves, orthopaedic implants, and indwelling catheters. Its biofilms are …

Current and future approaches to the prevention and treatment of staphylococcal medical device-related infections

S Hogan, NT Stevens, H Humphreys… - Current …, 2015 - ingentaconnect.com
Staphylococci, in particular Staphylococcus aureus and Staphylococcus epidermidis, are a
leading cause of healthcareassociated infections. Patients who have a medical device …

Biofilm Formation by Pathogenic Bacteria: Applying a Staphylococcus aureus Model to Appraise Potential Targets for Therapeutic Intervention

Z Sedarat, AW Taylor-Robinson - Pathogens, 2022 - mdpi.com
Carried in the nasal passages by up to 30% of humans, Staphylococcus aureus is
recognized to be a successful opportunistic pathogen. It is a frequent cause of infections of …

Staphylococcal biofilms: Challenges and novel therapeutic perspectives

C Kranjec, D Morales Angeles, M Torrissen Mårli… - Antibiotics, 2021 - mdpi.com
Staphylococci, like Staphylococcus aureus and S. epidermidis, are common colonizers of
the human microbiota. While being harmless in many cases, many virulence factors result in …

Current therapies and challenges for the treatment of Staphylococcus aureus biofilm‐related infections

NN Tran, T Morrisette, SCJ Jorgensen… - … : The Journal of …, 2023 - Wiley Online Library
Staphylococcus aureus is a major cause of nosocomial and community‐acquired infections
and contributes to significant increase in morbidity and mortality especially when associated …

Untangling the diverse and redundant mechanisms of Staphylococcus aureus biofilm formation

M Zapotoczna, E O'Neill, JP O'Gara - PLoS pathogens, 2016 - journals.plos.org
A major challenge in the management of device-related infections (DRIs) involving microbial
biofilms derives from the rapid coating of implanted biomaterials by host-derived …

Anti-biofilm agents: recent breakthrough against multi-drug resistant Staphylococcus aureus

PY Chung, YS Toh - Pathogens and disease, 2014 - academic.oup.com
Staphylococcus aureus is a Gram-positive pathogen that causes potentially life-threatening
nosocomial-and community-acquired infections, such as osteomyelitis and endocarditis …

Hiding in plain sight: interplay between staphylococcal biofilms and host immunity

TD Scherr, CE Heim, JM Morrison… - Frontiers in immunology, 2014 - frontiersin.org
Staphylococcus aureus and Staphylococcus epidermidis are notable for their propensity to
form biofilms on implanted medical devices. Staphylococcal biofilm infections are typified by …

New approaches for treating staphylococcal biofilm infections

MR Kiedrowski, AR Horswill - … of the New York Academy of …, 2011 - Wiley Online Library
Bacteria of the genus Staphylococcus are a prominent cause of acute and chronic infections.
The ability of the staphylococci to establish biofilms has been linked to the persistence of …