Autoregulatory expression of the Escherichia coli hns gene encoding a nucleoid protein: H-NS functions as a repressor of its own transcription

C Ueguchi, M Kakeda, T Mizuno - Molecular and General Genetics MGG, 1993 - Springer
The Escherichia coli nucleoid protein, H-NS (or H1a), appears to influence the regulation of
a variety of unrelated E. coli genes and operons. To gain an insight into the regulation of the …

Function of the Escherichia coli nucleoid protein, H-NS molecular analysis of a subset of proteins whose expression is enhanced in a hns deletion mutant

T Yoshida, C Ueguchi, H Yamada, T Mizuno - Molecular and General …, 1993 - Springer
The expression of numerous Escherichia coli cellular proteins was previously demonstrated
to be greatly enhanced in a hns deletion background, relative to the levels in wild-type cells …

The Escherichia coli nucleoid protein H‐NS functions directly as a transcriptional repressor.

C Ueguchi, T Mizuno - The EMBO journal, 1993 - embopress.org
The H‐NS protein is a major constituent of the Escherichia coli nucleoid structure and is
implicated in the compact organization of the chromosome. Based on recent genetic …

Coupling of Escherichia coli hns mRNA levels to DNA synthesis by autoregulation: implications for growth phase control

A Free, CJ Dorman - Molecular microbiology, 1995 - Wiley Online Library
The H‐NS protein of enteric bacteria is one of the major proteins of the bacterial nucleoid
and seems to play an important role in nucleoid structure. Transcription of the hns gene …

Expression of the gene encoding the major bacterial nucleoid protein H‐NS is subject to transcriptional auto‐repression

M Falconi, NP Higgins, R Spurio, CL Pon… - Molecular …, 1993 - Wiley Online Library
Expression of a promoterless cat gene fused to a DNA fragment of approximately 400 bp,
beginning at–313 of Escherichia coli hns, was significantly repressed in E. coli and …

Synthesis of the Escherichia coli K‐12 nucleoid‐associated DNA‐binding protein H‐NS is subjected to growth‐phase control and autoregulation

P Dersch, K Schmidt, E Bremer - Molecular Microbiology, 1993 - Wiley Online Library
Mutations in the structural gene (hns) for the Escherichia coli nucleoid‐associated DNA‐
binding protein H‐NS cause highly pleiotropic effects on gene expression, site‐specific …

Molecular aspects of the E. coli nucleoid protein, H-NS: a central controller of gene regulatory networks

RM Williams, S Rimsky - FEMS microbiology letters, 1997 - academic.oup.com
The nucleoid-associated protein H-NS has a central role in the structuring and control of the
enteric bacterial chromosome. This protein has been demonstrated to contribute to the …

Systematic Mutational Analysis Revealing the Functional Domain Organization ofEscherichia coliNucleoid Protein H-NS

C Ueguchi, T Suzuki, T Yoshida, K Tanaka… - Journal of molecular …, 1996 - Elsevier
TheEscherichia coliH-NS protein is one of the major constituents of the nucleoid structure.
This protein has been implicated not only in the compact organization of the nucleoid …

Clarification of the dimerization domain and its functional significance for the Escherichia coli nucleoid protein H-NS

C Ueguchi, C Seto, T Suzuki, T Mizuno - Journal of molecular biology, 1997 - Elsevier
The Escherichia coli nucleoid protein, H-NS, functions as a global regulator for expression of
a wide variety of genes. We recently analyzed the structure-function relationship of H-NS …

Modulated expression of promoters containing upstream curved DNA sequences by the Escherichia coli nucleoid protein H‐NS

F Zuber, D Kotlarz, S Rimsky, H Buc - Molecular microbiology, 1994 - Wiley Online Library
Replacement of the CRP‐binding site of the gal control region by curved sequences can
lead to the restoration of promoter strength in vivo. One curved sequence called 5A6A …