Unique somatic and malignant expression patterns implicate PIWI-interacting RNAs in cancer-type specific biology
Abstract Human PIWI-interacting RNAs (piRNAs) are known to be expressed in germline
cells, functionally silencing LINEs and SINEs. Their expression patterns in somatic tissues …
cells, functionally silencing LINEs and SINEs. Their expression patterns in somatic tissues …
PIWI-interacting RNAs: critical roles and therapeutic targets in cancer
J Zhou, H Xie, J Liu, R Huang, Y Xiang, D Tian, E Bian - Cancer Letters, 2023 - Elsevier
P-element-induced wimpy testis (PIWI)-interacting RNAs (piRNAs) are a novel class of small
regulatory RNAs (approximately 24–31 nucleotides in length) that often bind to members of …
regulatory RNAs (approximately 24–31 nucleotides in length) that often bind to members of …
Piwi-interacting RNAs in cancer: emerging functions and clinical utility
PIWI-interacting RNAs (piRNAs) are emerging players in cancer genomics. Originally
described in the germline, there are over 20,000 piRNA genes in the human genome. In …
described in the germline, there are over 20,000 piRNA genes in the human genome. In …
The emerging roles of PIWI-interacting RNA in human cancers
Y Yu, J Xiao, SS Hann - Cancer Management and Research, 2019 - Taylor & Francis
PIWI-interacting RNAs (piRNAs) are a type of non-coding RNAs that interact with PIWI
proteins, which are members of the argonaute family. Originally described in the germline …
proteins, which are members of the argonaute family. Originally described in the germline …
Piwi-interacting RNAs (piRNAs) and cancer: Emerging biological concepts and potential clinical implications
W Weng, H Li, A Goel - Biochimica et Biophysica Acta (BBA)-Reviews on …, 2019 - Elsevier
Piwi-interacting RNAs (piRNAs) are a very recently discovered class of small non-coding
RNAs (ncRNAs), with approximately 20,000 piRNA genes already identified within the …
RNAs (ncRNAs), with approximately 20,000 piRNA genes already identified within the …
The emerging role of the piRNA/piwi complex in cancer
Y Liu, M Dou, X Song, Y Dong, S Liu, H Liu, J Tao, W Li… - Molecular cancer, 2019 - Springer
Piwi interacting RNAs (piRNAs) constitute novel small non-coding RNA molecules of
approximately 24–31 nucleotides in length that often bind to members of the piwi protein …
approximately 24–31 nucleotides in length that often bind to members of the piwi protein …
Piwi-interacting RNAs (piRNAs) are dysregulated in renal cell carcinoma and associated with tumor metastasis and cancer-specific survival
Piwi-interacting RNAs (piRNAs) are a distinct group of small noncoding RNAs (sncRNAs)
that silence transposable genetic elements to protect genome integrity. Because of their …
that silence transposable genetic elements to protect genome integrity. Because of their …
The biogenesis and biological function of PIWI-interacting RNA in cancer
S Chen, S Ben, J Xin, S Li, R Zheng, H Wang… - Journal of hematology & …, 2021 - Springer
Small non-coding RNAs (ncRNAs) are vital regulators of biological activities, and aberrant
levels of small ncRNAs are commonly found in precancerous lesions and cancer. PIWI …
levels of small ncRNAs are commonly found in precancerous lesions and cancer. PIWI …
PIWI-interacting RNA 021285 is involved in breast tumorigenesis possibly by remodeling the cancer epigenome
Abstract Although PIWI-interacting RNAs (piRNAs) account for the largest class of the small
non-coding RNA superfamily, virtually nothing is known of their function in human …
non-coding RNA superfamily, virtually nothing is known of their function in human …
Novel evidence for a PIWI-interacting RNA (piRNA) as an oncogenic mediator of disease progression, and a potential prognostic biomarker in colorectal cancer
W Weng, N Liu, Y Toiyama, M Kusunoki, T Nagasaka… - Molecular cancer, 2018 - Springer
Background Emerging evidence suggests that PIWI-interacting RNAs (piRNAs) may be
important epigenetic regulators of gene expression in human cancers; however, their …
important epigenetic regulators of gene expression in human cancers; however, their …