Endogenous and Exogenous Opioids: Role in Substance Use Disorders
L Acree - Endogenous Opioids: From Basic Science to …, 2024 - Springer
Opioid use disorders have become an epidemic in recent years with rates nearly
quadrupling since 1999 according to the US Centers for Disease Control and Prevention …
quadrupling since 1999 according to the US Centers for Disease Control and Prevention …
Analysis of the genetic and neurological components of opioid addiction, with public health perspectives of the opioid epidemic in the United States of America
JA Dubhashi - DISCOVERY: Georgia State Honors College …, 2019 - scholarworks.gsu.edu
Opioid addiction has reached epidemic levels around the world, with over-prescription of
opioid pain relievers being an often-cited reason for the epidemic in the USA. This project …
opioid pain relievers being an often-cited reason for the epidemic in the USA. This project …
Endogenous opioid system in addiction and addiction-related behaviors
B Reed, ER Butelman, MJ Kreek - Current opinion in behavioral sciences, 2017 - Elsevier
Highlights•Alterations in endogenous opioid system components occur in development of
addiction.•Human studies and animal models show opioid genes contribute to addiction …
addiction.•Human studies and animal models show opioid genes contribute to addiction …
[HTML][HTML] The molecular neurobiology and neuropathology of opioid use disorder
CA Blackwood, JL Cadet - Current research in neurobiology, 2021 - Elsevier
The number of people diagnosed with opioid use disorder has skyrocketed as a
consequence of the opioid epidemic and the increased prescribing of opioid drugs for …
consequence of the opioid epidemic and the increased prescribing of opioid drugs for …
The genetics of the opioid system and specific drug addictions
O Levran, V Yuferov, MJ Kreek - Human genetics, 2012 - Springer
Addiction to drugs is a chronic, relapsing brain disease that has major medical, social, and
economic complications. It has been established that genetic factors contribute to the …
economic complications. It has been established that genetic factors contribute to the …
Epigenetic and genetic factors associated with opioid use disorder: are these relevant to African American populations
CA Blackwood, JL Cadet - Frontiers in Pharmacology, 2021 - frontiersin.org
In the United States, the number of people suffering from opioid use disorder has
skyrocketed in all populations. Nevertheless, observations of racial disparities amongst …
skyrocketed in all populations. Nevertheless, observations of racial disparities amongst …
[图书][B] The Oxford Handbook of Opioids and Opioid Use Disorder
KE Dunn - 2024 - books.google.com
Opioids have played a prominent role in society for centuries and have been lauded for both
their analgesic and euphoric qualities by cultures throughout the world. The advent of …
their analgesic and euphoric qualities by cultures throughout the world. The advent of …
Epigenetic mechanisms of opioid addiction
Opioid use kills tens of thousands of Americans each year, devastates families and entire
communities, and cripples the health care system. Exposure to opioids causes long-term …
communities, and cripples the health care system. Exposure to opioids causes long-term …
Drug dependence and the endogenous opioid system
MAFM Gerrits, HBM Lesscher, JM van Ree - European …, 2003 - Elsevier
The discovery of endogenous opioids has markedly influenced the research on the biology
of drug dependence. Evidence has been presented that these brain substances are self …
of drug dependence. Evidence has been presented that these brain substances are self …
Endogenous opioids at the intersection of opioid addiction, pain, and depression: the search for a precision medicine approach
Opioid addiction and overdose are at record levels in the United States. This is driven, in
part, by their widespread prescription for the treatment of pain, which also increased …
part, by their widespread prescription for the treatment of pain, which also increased …