In ciliates, different microtubular structures are nucleated from diverse Microtubule
Organizing Centers (MTOCs). γ-Tubulin is a tubulin superfamily member that plays an …

Background The multi-tubulin hypothesis proposes that each tubulin isotype performs a
unique role, or subset of roles, in the universe of microtubule function (s). To test this …

The mechanisms that regulate γ‐tubulin, including its post‐translational modifications, are
poorly understood. γ‐Tubulin is important for the duplication of centrioles and structurally …

α‐Tubulin microheterogeneity was studied in Tetrahymena pyriformis. Using two‐
dimensional electrophoretic analysis, we found between five and seven α‐tubulin and four β …

The single alpha‐tubulin gene of Tetrahymena thermophila was isolated from a genomic
library and shown to encode a single protein. Comparisons of the rates of evolution of this …

Thanks to recent technological advances, the ciliate Tetrahymena thermophila has emerged
as an attractive model organism for studies on the assembly of microtubular organelles in a …

The ciliate Tetrahymena pyriformis contains one α‐tubulin (αTT) and two β‐tubulin (βTT1
and βTT2) genes. The specific expression of these genes was investigated by Northern blot …

Basal bodies and centrioles are conserved microtubule-based organelles the improper
assembly of which leads to a number of diseases, including ciliopathies and cancer. Tubulin …

Macronuclear DNA of the ciliate Tetrahymena pyriformis contains only one size class of
fragments coding for α-tubulin, αTT. We have isolated αTT from a partial plasmid library …

Tetrahymena and Paramecium species are widely used representatives of the phylum
Ciliata. Ciliates are particularly suitable model organisms for studying the functional …