Calcium dyshomeostasis in Alzheimer's disease pathogenesis
R Cascella, C Cecchi - International journal of molecular sciences, 2021 - mdpi.com
Alzheimer's disease (AD) is the most common age-related neurodegenerative disorder that
is characterized by amyloid β-protein deposition in senile plaques, neurofibrillary tangles …
is characterized by amyloid β-protein deposition in senile plaques, neurofibrillary tangles …
Current progress, challenges and future prospects of diagnostic and therapeutic interventions in Alzheimer's disease
K Rajasekhar, T Govindaraju - RSC advances, 2018 - pubs.rsc.org
Alzheimer's disease (AD) is the most prevalent, progressive and multifaceted
neurodegenerative disorder associated with cognition, memory and behavioural …
neurodegenerative disorder associated with cognition, memory and behavioural …
Microtubule-associated protein tau as a therapeutic target in Alzheimer's disease
Introduction: Alzheimer's disease (AD) is a major public health problem in modern society
and as yet, other than a few symptomatic drugs, there is no disease-modifying treatment for …
and as yet, other than a few symptomatic drugs, there is no disease-modifying treatment for …
[PDF][PDF] Alzheimer's Disease Puzzle: Delving into Pathogenesis Hypotheses.
Alzheimer's disease (AD) is a prevalent neurodegenerative disease characterized by both
amnestic and non-amnestic clinical manifestations. It accounts for approximately 60-70% of …
amnestic and non-amnestic clinical manifestations. It accounts for approximately 60-70% of …
Pivotal role of glycogen synthase kinase-3: a therapeutic target for Alzheimer's disease
Neurodegenerative diseases are among the most challenging diseases with poorly known
mechanism of cause and paucity of complete cure. Out of all the neurodegenerative …
mechanism of cause and paucity of complete cure. Out of all the neurodegenerative …
Can we treat neuroinflammation in Alzheimer's disease?
S Sánchez-Sarasúa, I Fernández-Pérez… - International Journal of …, 2020 - mdpi.com
Alzheimer's disease (AD), considered the most common type of dementia, is characterized
by a progressive loss of memory, visuospatial, language and complex cognitive abilities. In …
by a progressive loss of memory, visuospatial, language and complex cognitive abilities. In …
cAMP-dependent protein kinase phosphorylations on tau in Alzheimer's disease
GA Jicha, C Weaver, E Lane, C Vianna… - Journal of …, 1999 - Soc Neuroscience
To elucidate the role cAMP-dependent protein kinase (PKA) phosphorylations on tau play in
Alzheimer's disease, we have generated highly specific monoclonal antibodies, CP-3 and …
Alzheimer's disease, we have generated highly specific monoclonal antibodies, CP-3 and …
Two decades of new drug discovery and development for Alzheimer's disease
Z Liu, A Zhang, H Sun, Y Han, L Kong, X Wang - RSC advances, 2017 - pubs.rsc.org
Alzheimer's disease is a progressive and irreversible neurodegenerative disease,
associated with a decreased cognitive function and severe behavioral abnormalities. Due to …
associated with a decreased cognitive function and severe behavioral abnormalities. Due to …
A review on Alzheimer's disease pathophysiology and its management: an update
A Kumar, A Singh - Pharmacological reports, 2015 - Elsevier
Alzheimer's disease acknowledged as progressive multifarious neurodegenerative disorder,
is the leading cause of dementia in late adult life. Pathologically it is characterized by …
is the leading cause of dementia in late adult life. Pathologically it is characterized by …
PI3K/AKT signaling mediated by G protein‑coupled receptors is involved in neurodegenerative Parkinson's disease
N Nakano, S Matsuda, M Ichimura… - International …, 2017 - spandidos-publications.com
Parkinson's disease (PD) is a common progressive and multifactorial neurodegenerative
disease, characterized by the loss of midbrain dopaminergic neurons. Numerous …
disease, characterized by the loss of midbrain dopaminergic neurons. Numerous …