Emerging technologies and platforms for the immunodetection of multiple biochemical markers in osteoarthritis research and therapy
E Bernotiene, E Bagdonas, G Kirdaite… - Frontiers in …, 2020 - frontiersin.org
Biomarkers, especially biochemical markers, are important in osteoarthritis (OA) research,
clinical trials, and drug development and have potential for more extensive use in …
clinical trials, and drug development and have potential for more extensive use in …
[HTML][HTML] Application of biomarkers in the development of drugs intended for the treatment of osteoarthritis
VB Kraus, B Burnett, J Coindreau, S Cottrell… - Osteoarthritis and …, 2011 - Elsevier
OBJECTIVE: Osteoarthritis (OA) is a chronic and slowly progressive disease for which
biomarkers may be able to provide a more rapid indication of therapeutic responses to …
biomarkers may be able to provide a more rapid indication of therapeutic responses to …
The evolving role of biomarkers for osteoarthritis
M Ishijima, H Kaneko, K Kaneko - Therapeutic advances in …, 2014 - journals.sagepub.com
Osteoarthritis (OA) is an increasingly important public health concern as the prevalence of
this disease becomes higher and higher due to the ageing population. However, in addition …
this disease becomes higher and higher due to the ageing population. However, in addition …
Recent progress toward biomarker identification in osteoarthritis
F De Ceuninck, M Sabatini, P Pastoureau - Drug discovery today, 2011 - Elsevier
Osteoarthritis (OA), the most common and disabling form of arthritic disease, is characterized
by a slow and progressive degeneration of articular cartilage. Its etiology is multifactorial and …
by a slow and progressive degeneration of articular cartilage. Its etiology is multifactorial and …
Biomarkers: in combination they may do better
FMK Williams - Arthritis research & therapy, 2009 - Springer
The field of biomarkers is a growing one, particularly in osteoarthritis (OA). OA is the most
common disabling condition in older persons and a major cause of morbidity. While the …
common disabling condition in older persons and a major cause of morbidity. While the …
Molecular taxonomy of osteoarthritis for patient stratification, disease management and drug development: biochemical markers associated with emerging clinical …
A Mobasheri, WE van Spil, E Budd… - Current opinion in …, 2019 - journals.lww.com
In this review, we have focused on the molecular biomarkers of four distinct osteoarthritis
subtypes including inflammatory, subchondral bone remodelling, metabolic syndrome and …
subtypes including inflammatory, subchondral bone remodelling, metabolic syndrome and …
[HTML][HTML] Defining the osteoarthritis patient: back to the future
The history of osteoarthritis (OA) is important because it can help broaden our perspective
on past and present controversies. The naming of OA, beginning with Heberden's nodes, is …
on past and present controversies. The naming of OA, beginning with Heberden's nodes, is …
Review of soluble biomarkers of osteoarthritis: lessons from animal models
CB Legrand, CJ Lambert, FV Comblain… - Cartilage, 2017 - journals.sagepub.com
Objective Osteoarthritis (OA) is one of the leading causes of disability within the adult
population. Currently, its diagnosis is mainly based on clinical examination and standard …
population. Currently, its diagnosis is mainly based on clinical examination and standard …
inflammation and biomarkers in osteoarthritis
Osteoarthritis (OA) is the most common form of arthritis affecting more than 500 million
people globally (1). It accounts for more pain and functional disability than any other …
people globally (1). It accounts for more pain and functional disability than any other …
Biomarkers of osteoarthritis—a narrative review on causal links with metabolic syndrome
Development of OA (OA) is multifactorial and is strongly associated with risk factors such as
aging, trauma, metabolic disorders, and obesity. Metabolic Syndrome (MetS)-associated OA …
aging, trauma, metabolic disorders, and obesity. Metabolic Syndrome (MetS)-associated OA …