An analysis of 14 molecular markers for monitoring osteoarthritis. Relationship of the markers to clinical end-points

IG Otterness, E Weiner, AC Swindell… - Osteoarthritis and …, 2001 - Elsevier
Objective To investigate whether any of 14 serum and urine molecular markers (MMs) used
to monitor osteoarthritis (OA) would be associated with particular clinical end-points. Design …

[HTML][HTML] Osteoarthritis–a case for personalized health care?

MA Karsdal, C Christiansen, C Ladel… - Osteoarthritis and …, 2014 - Elsevier
For both economic and ethical reasons, identification of the optimal treatment for each
individual patient is a pressing concern, not only for the patients and their physician, but also …

[HTML][HTML] New horizons in osteoarthritis

F Oliviero, R Ramonda, L Punzi - Swiss medical weekly, 2010 - smw.ch
Osteoarthritis (OA), also known as degenerative joint disease, is the most frequent chronic
musculoskeletal disease and the leading cause of disability in elderly persons. There are …

[HTML][HTML] Towards precision medicine for osteoarthritis: focus on the synovial fluid proteome

L Moretti, D Bizzoca, A Geronimo, FL Moretti… - International Journal of …, 2022 - mdpi.com
Osteoarthritis (OA) is a joint degenerative disease that most affects old age. The study of
proteomics in synovial fluid (SF) has the task of providing additional elements to diagnose …

[HTML][HTML] Osteoarthritis year in review 2017: genetics and epigenetics

MJ Peffers, P Balaskas, A Smagul - Osteoarthritis and cartilage, 2018 - Elsevier
Objective The purpose of this review is to describe highlights from original research
publications related to osteoarthritis (OA), epigenetics and genomics with the intention of …

[HTML][HTML] Osteoarthritis: pathogenic signaling pathways and therapeutic targets

Q Yao, X Wu, C Tao, W Gong, M Chen, M Qu… - Signal transduction and …, 2023 - nature.com
Osteoarthritis (OA) is a chronic degenerative joint disorder that leads to disability and affects
more than 500 million population worldwide. OA was believed to be caused by the wearing …

[HTML][HTML] Recent advances in understanding the phenotypes of osteoarthritis

A Mobasheri, S Saarakkala, M Finnilä… - …, 2019 - ncbi.nlm.nih.gov
Recent research in the field of osteoarthritis (OA) has focused on understanding the
underlying molecular and clinical phenotypes of the disease. This narrative review article …

[HTML][HTML] Osteoarthritis year in review 2013: biology

RF Loeser - Osteoarthritis and Cartilage, 2013 - Elsevier
The purpose of this review was to present highlights from the published literature on the
topic of the biology of osteoarthritis (OA). A PubMed search was conducted in order to locate …

[HTML][HTML] Can we identify patients with high risk of osteoarthritis progression who will respond to treatment? A focus on epidemiology and phenotype of osteoarthritis

O Bruyere, C Cooper, N Arden, J Branco, ML Brandi… - Drugs & aging, 2015 - Springer
Osteoarthritis is a syndrome affecting a variety of patient profiles. A European Society for
Clinical and Economic Aspects of Osteoporosis and Osteoarthritis and the European Union …

[HTML][HTML] Can we identify patients with high risk of osteoarthritis progression who will respond to treatment? A focus on biomarkers and frailty

N Arden, P Richette, C Cooper, O Bruyère, E Abadie… - Drugs & aging, 2015 - Springer
Osteoarthritis (OA), a disease affecting different patient phenotypes, appears as an optimal
candidate for personalized healthcare. The aim of the discussions of the European Society …