Nanoparticles are under investigation as diagnostic and therapeutic agents for joint
diseases, such as osteoarthritis. However, there is incomplete understanding of nanoparticle …

Understanding nanoparticle diffusion within non-Newtonian biological and synthetic fluids is
essential in designing novel formulations (eg, nanomedicines for drug delivery, shampoos …

Hyaluronic acid is an abundant polyelectrolyte in the human body that forms extracellular
hydrogels in connective tissues. It is essential for regulating tissue biomechanics and cell …

We examine the dynamics of silica particles grafted with high molecular weight polystyrene
suspended in semidilute solutions of chemically similar linear polymer using X-ray photon …

It is shown that the rotational diffusivity of nanoparticles in polymer solutions spanning the
dilute to semi-dilute regimes deviates from the predictions of the Stokes–Einstein (SE) …

Purpose To evaluate using cationic polymeric nanoparticles that interact with hyaluronate to
form ionically cross-linked hydrogels to increase the intra-articular retention time of …

Developing effective therapeutics for osteoarthritis (OA) necessitates that such molecules
can reach and target chondrocytes within articular cartilage. However, predicting how well …

A major hurdle limiting the ability to treat and cure osteoarthritis, a common and debilitating
disease, is rapid joint clearance and limited cartilage targeting of intra-articular therapies …

The diffusion of poly (ethylene glycol) methyl ether thiol (PEGSH)-functionalized gold
nanoparticles (NPs) was measured in polyacrylamide gels with various cross-linking …

Flow of viscoelastic fluids in porous media is ubiquitous in biological and industrial
processes, and the choice of viscoelastic fluids is of foremost importance for their effect on …