Osteogenesis imperfecta is a genetic disorder that causes increased bone fragility and low
bone mass. Osteogenesis imperfecta is a rare disease: its estimated prevalence is between …

Osteogenesis imperfecta is a group of inherited diseases responsible for varying degrees of
skeletal fragility. Minimal trauma is sufficient to cause fractures and bone deformities. The …

Osteogenesis imperfecta is a rare hereditary disease mostly caused by mutations impairing
collagen synthesis and modification. Recently recessive forms have been described …

Osteogenesis imperfecta is the most common inherited form of bone disease resulting in
osteoporosis in childhood. Progress in the field has been swift over the last decade with the …

Considerable progress has been made in many aspects of osteogenesis imperfecta. The
international Sillence classification of osteogenesis imperfecta is being expanded to include …

Osteogenesis imperfecta (OI) comprises a group of disorders principally affecting type I
collagen which result in increased bone fragility. Children with severe OI suffer recurrent …

Abstract “Osteogenesis imperfecta” is a term used to describe a group of genetic disorders of
variable phenotype usually defined by recurrent fractures, low bone mass, and skeletal …

Osteogenesis Imperfecta (OI) is characterized by bone fragility. At least seven discrete types
have been described ranging from mild disease to a lethal form. In a large number of cases …

Osteogenesis imperfecta (OI) is a heterogeneous group of disorders principally affecting
type I collagen. Children with the severe forms of the condition suffer recurrent fractures …

The last 2 years have seen additions proposed to the very limited armamentarium of
treatments for osteogenesis imperfecta. These include the use of bisphosphonates to …