A review of the pharmacology of carbonic anhydrase inhibitors for the treatment of glaucoma in dogs and cats

T Maślanka - The Veterinary Journal, 2015 - Elsevier
Glaucoma is a heterogeneous group of disorders usually associated with elevated
intraocular pressure (IOP), leading to optic nerve damage, retinal ganglion cell death and …

Medical anti‐glaucoma therapy: Beyond the drop

PE Miller, JS Eaton - Veterinary ophthalmology, 2021 - Wiley Online Library
Barriers to effective medical therapy are numerous and include difficulties with effective and
sustained control of intraocular pressure (IOP) and adherence to prescribed anti‐glaucoma …

Effects of topical administration of 1% brinzolamide on intraocular pressure in clinically normal horses

SE Germann, FL Matheis, A Rampazzo… - Equine veterinary …, 2008 - Wiley Online Library
Reasons for performing study: Only few drugs with limited efficacy are available for topical
treatment of equine glaucoma. Objective: To evaluate the effect of topical administration of …

Changes in intraocular pressure associated with topical dorzolamide and oral methazolamide in glaucomatous dogs

KN Gelatt, EO MacKay - Veterinary ophthalmology, 2001 - Wiley Online Library
Objective To compare the reduction in intraocular pressure (IOP) by topical 2% dorzolamide
to oral methazolamide (5 mg/kg) in dogs, and determine if the combination of both drugs …

Ophthalmic medications and therapeutics

DJ Maggs - Slatter's Fundamentals of Veterinary Ophthalmology, 2017 - books.google.com
A drug may be administered by multiple routes to treat ocular (ie, adnexal, ocular surface,
intraocular, or orbital) disease. These routes are shown in Figure 3-1 and include the …

Canine glaucoma: pathophysiology and diagnosis.

S Reinstein, A Rankin, R Allbaugh - Compendium (Yardley, PA), 2009 - europepmc.org
Canine glaucoma encompasses a diverse group of diseases associated with an increase in
intraocular pressure that results in retinal ganglion cell death and eventual blindness. Dogs …

[PDF][PDF] Does that drug work? Pitfalls in studies on the efficacy and safety of glaucoma medications

CB Camras, D Minckler - American Journal of Ophthalmology, 2000 - academia.edu
IN A PERFECT WORLD, THE EFFICACY OF THERAPEUTIC agents for glaucoma would be
determined through large, well-planned, randomized controlled trials (RCTs), placebo …

The effect of prophylactic topical carbonic anhydrase inhibitors in canine primary closed‐angle glaucoma

R Stavinohova, JR Newton… - Journal of Small Animal …, 2015 - Wiley Online Library
OBJECTIVES To determine the effect of 1% brinzolamide, 2% dorzolamide hydrochloride or
combination 2% dorzolamide hydrochloride/0· 5% timolol to delay the elevation of the …

Advances in glaucoma therapeutics

IH Pang, AF Clark - Expert opinion on emerging drugs, 2002 - Taylor & Francis
Glaucoma is a major cause of irreversible blindness in the world. The prevalence of
glaucomatous loss in vision will continue to grow as our populations age. Ocular …

Definition, classification, and pathophysiology of canine glaucoma

S Pizzirani - Veterinary Clinics: Small Animal Practice, 2015 - vetsmall.theclinics.com
Glaucoma is a heterogeneous group of progressive disorders characterized by retinal
ganglion cell (RGC) apoptosis and a specific optic neuropathy (glaucomatous optic …