Empowered by recent advances of sequencing techniques, transcriptome-wide studies have
characterized over 150 different types of post-transcriptional chemical modifications of RNA …

The activity of RNA is controlled by different types of post-transcriptional modifications, such
as the addition of methyl groups and other chemical and structural changes, that have been …

The epigenetic landscape has an important role in cellular homeostasis and its deregulation
leads to cancer. Noncoding (nc) RNA networks function as major regulators of cellular …

While only a small part of the human genome encodes for proteins, biological functions for
the so-called junk genome are increasingly being recognized through high-throughput …

The central dogma of molecular biology states that the functions of RNA revolve around
protein translation. Until the last decade, most researches were geared towards …

The discovery of the role of non-coding RNAs (ncRNAs) in the onset and progression of
malignancies is a promising frontier of cancer genetics. It is clear that ncRNAs are …

New discoveries and accelerating progresses in the field of noncoding RNAs (ncRNAs)
continuously challenges our deep-rooted doctrines in biology and sometimes our …

Nearly all classes of coding and non-coding RNA undergo post-transcriptional modification,
as more than 150 distinct modification types have been reported. Since RNA modifications …

Long noncoding RNAs (lncRNAs) constitute large portions of the mammalian transcriptome
which appeared as a fundamental player, regulating various cellular mechanisms. LncRNAs …

As next-generation sequencing (NGS) is leaping forward, more than 160 covalent RNA
modification processes have been reported, and they are widely present in every organism …