Application and innovation of multiomics technologies in clinical oncology

X Li, A Budzin, Y Wang - Frontiers in Oncology, 2023 - frontiersin.org
Cancer is a complex disease that involves multiple layers of genetic, epigenetic, and
metabolic alterations and interactions to orchestrate tumor growth and progression …

The need for multi-omics biomarker signatures in precision medicine

M Olivier, R Asmis, GA Hawkins, TD Howard… - International journal of …, 2019 - mdpi.com
Recent advances in omics technologies have led to unprecedented efforts characterizing
the molecular changes that underlie the development and progression of a wide array of …

Multiomics approaches in cancer

H Hameed, S Faheem, M Zaman, MA Khan… - Biological Insights of …, 2024 - Elsevier
The burden of cancer on global public health is substantial. Despite advancements in
treatment options, the underlying mechanisms and precise molecular pathways involved in …

Molecular and multi-omic approaches in understanding cancer biology and anticancer therapies: current perspectives and new challenges

BA Abdel-Wahab, YA Helmy, EM Saied - Frontiers in Pharmacology, 2023 - frontiersin.org
A holistic understanding of cancer biology and pathophysiological features is crucial. Multi-
omics approaches integrate multiple datasets to understand cancer molecular and clinical …

[DOC][DOC] Multi-OMICS approach for biomarker discovery in cancer

A Swain, A Pradhan, SR Jena, D Soren, L Samanta - iipseries.org
Despite significant progress in the recent past, cancer remains as an enigma for both
clinicians and scientists alike and the underlying mechanism (s) of onset and progression of …

The crucial role of multiomic approach in cancer research and clinically relevant outcomes

M Lu, X Zhan - EPMA Journal, 2018 - Springer
Cancer with heavily economic and social burden is the hot point in the field of medical
research. Some remarkable achievements have been made; however, the exact …

From single level analysis to multi-omics integrative approaches: a powerful strategy towards the precision oncology

MEG Cantafio, K Grillone, D Caracciolo… - The Road from …, 2019 - taylorfrancis.com
This chapter discusses general concepts on the generation of omics data, along with
available strategies for multi-omics data analysis and integration in the context of clinical …

Onco‐multi‐OMICS approach: a new frontier in cancer research

S Chakraborty, MI Hosen, M Ahmed… - BioMed research …, 2018 - Wiley Online Library
The acquisition of cancer hallmarks requires molecular alterations at multiple levels
including genome, epigenome, transcriptome, proteome, and metabolome. In the past …

Artificial intelligence-based multi-omics analysis fuels cancer precision medicine

X He, X Liu, F Zuo, H Shi, J Jing - Seminars in Cancer Biology, 2023 - Elsevier
With biotechnological advancements, innovative omics technologies are constantly
emerging that have enabled researchers to access multi-layer information from the genome …

Multi-omics analysis: Paving the path toward achieving precision medicine in cancer treatment and immuno-oncology

V Raufaste-Cazavieille, R Santiago… - Frontiers in Molecular …, 2022 - frontiersin.org
The acceleration of large-scale sequencing and the progress in high-throughput
computational analyses, defined as omics, was a hallmark for the comprehension of the …