Curious entanglements: interactions between mosquitoes, their microbiota, and arboviruses

EP Caragata, CV Tikhe, G Dimopoulos - Current opinion in virology, 2019 - Elsevier
Highlights•The mosquito microbiota plays a modulatory role in arbovirus transmission.•
Mosquito–microbiota–virus interactions are diverse and poorly characterized.•Elucidating …

The microbiome modulates arbovirus transmission in mosquitoes

S Hegde, JL Rasgon, GL Hughes - Current opinion in virology, 2015 - Elsevier
Highlights•Complex interactions occur within the mosquito holobiome that profoundly alter
the phenotype of the host.•Bacteria can enhance or suppress arbovirus transmission in …

The mosquito microbiota influences vector competence for human pathogens

NJ Dennison, N Jupatanakul, G Dimopoulos - Current opinion in insect …, 2014 - Elsevier
Highlights•The midgut of mosquito disease vectors contains a diverse microbial flora.•The
microbiota can modulate the mosquito immune response and influence vector competence …

Bidirectional Interactions between Arboviruses and the Bacterial and Viral Microbiota in Aedes aegypti and Culex quinquefasciatus

C Shi, L Beller, L Wang, A Rosales Rosas… - MBio, 2022 - Am Soc Microbiol
Mosquitoes are important vectors for many arboviruses. It is becoming increasingly clear that
various symbiotic microorganisms (including bacteria and insect-specific viruses; ISVs) in …

[HTML][HTML] A gut commensal bacterium promotes mosquito permissiveness to arboviruses

P Wu, P Sun, K Nie, Y Zhu, M Shi, C Xiao, H Liu, Q Liu… - Cell host & …, 2019 - cell.com
Mosquitoes are hematophagous vectors that can acquire human viruses in their intestinal
tract. Here, we define a mosquito gut commensal bacterium that promotes permissiveness to …

Progress towards understanding the mosquito-borne virus life cycle

X Yu, Y Zhu, X Xiao, P Wang, G Cheng - Trends in parasitology, 2019 - cell.com
Mosquito-borne arboviruses are a group of heterogeneous viruses that are mainly
transmitted to vertebrate hosts and are the aetiological agents of many human diseases …

Mosquito microbiota and implications for disease control

H Gao, C Cui, L Wang, M Jacobs-Lorena, S Wang - Trends in parasitology, 2020 - cell.com
Mosquito-transmitted diseases account for about 500 000 deaths every year. Blocking these
pathogens in the mosquito vector before they are transmitted to humans is an effective …

Bacteria and antiviral immunity in insects

KN Johnson - Current opinion in insect science, 2015 - Elsevier
Highlights•Bacteria isolated from mosquitoes modulate virus infection, including dengue and
La Crosse virus.•Wolbachia mediates antiviral protection in both mosquitoes and …

Impact of the microbiome on mosquito-borne diseases

H Shi, X Yu, G Cheng - Protein & Cell, 2023 - academic.oup.com
Mosquito-borne diseases present a significant threat to human health, with the possibility of
outbreaks of new mosquito-borne diseases always looming. Unfortunately, current …

Understanding the Wolbachia-mediated inhibition of arboviruses in mosquitoes: progress and challenges

SM Rainey, P Shah, A Kohl… - Journal of General …, 2014 - microbiologyresearch.org
Arthropod-borne viruses (arboviruses) pose a considerable threat to human and animal
health, yet effective control measures have proven difficult to implement, and novel means of …