Dietary feeding of grape seed extract prevents intestinal tumorigenesis in APCmin/+ mice
B Velmurugan, RP Singh, N Kaul, R Agarwal… - Neoplasia, 2010 - Elsevier
Chemopreventive effects and associated mechanisms of grape seed extract (GSE) against
intestinal/colon cancer development are largely unknown. Herein, we investigated GSE …
intestinal/colon cancer development are largely unknown. Herein, we investigated GSE …
Grape Seed Extract Inhibits In vitro and In vivo Growth of Human Colorectal Carcinoma Cells
M Kaur, RP Singh, M Gu, R Agarwal, C Agarwal - Clinical Cancer Research, 2006 - AACR
Purpose: Accumulating evidences suggest the beneficial effects of fruit-and-vegetable
consumption in lowering the risk of various cancers, including colorectal cancer. Herein, we …
consumption in lowering the risk of various cancers, including colorectal cancer. Herein, we …
Grape antioxidant dietary fiber inhibits intestinal polyposis in Apc Min/+ mice: relation to cell cycle and immune response
S Sánchez-Tena, D Lizárraga, A Miranda… - …, 2013 - academic.oup.com
Epidemiological and experimental studies suggest that fiber and phenolic compounds might
have a protective effect on the development of colon cancer in humans. Accordingly, we …
have a protective effect on the development of colon cancer in humans. Accordingly, we …
Dietary‐feeding of grape seed extract prevents azoxymethane‐induced colonic aberrant crypt foci formation in fischer 344 rats
B Velmurugan, RP Singh, R Agarwal… - Molecular …, 2010 - Wiley Online Library
Chemoprevention by dietary agents/supplements has emerged as a novel approach to
control various malignancies, including colorectal cancer (CRC). This study assessed …
control various malignancies, including colorectal cancer (CRC). This study assessed …
Grape seed extract induces cell cycle arrest and apoptosis in human colon carcinoma cells
M Kaur, R Mandair, R Agarwal, C Agarwal - Nutrition and cancer, 2008 - Taylor & Francis
One approach to control colorectal cancer (CRC) is its preventive intervention by dietary
agents or those consumed as supplements. However, because most of these products are …
agents or those consumed as supplements. However, because most of these products are …
Grape pomace inhibits colon carcinogenesis by suppressing cell proliferation and inducing epigenetic modifications
Grape pomace (GP), a by-product of the wine and juice industry, is rich in bioflavonoids and
dietary fibers. We hypothesized that GP has protective effects against colitis-associated …
dietary fibers. We hypothesized that GP has protective effects against colitis-associated …
Grape seed extract efficacy against azoxymethane-induced colon tumorigenesis in A/J mice: interlinking miRNA with cytokine signaling and inflammation
Colorectal cancer (CRC) is the second leading cause of cancer-associated deaths,
suggesting that additional strategies are needed to prevent/control this malignancy. As CRC …
suggesting that additional strategies are needed to prevent/control this malignancy. As CRC …
A flavonoid-rich extract from bergamot juice prevents carcinogenesis in a genetic model of colorectal cancer, the Pirc rat (F344/NTac-Apcam1137)
Purpose To determine the potential of a flavonoid-rich extract from bergamot juice (BJe) to
prevent colorectal carcinogenesis (CRC) in vivo. Main methods Pirc rats (F344/NTac-Apc …
prevent colorectal carcinogenesis (CRC) in vivo. Main methods Pirc rats (F344/NTac-Apc …
Grape seeds and skin induce tumor growth inhibition via G1-phase arrest and apoptosis in mice inoculated with Ehrlich ascites carcinoma
Objectives Chemoprevention or intervention of cancer by means of natural dietary
components has shown great promise in controlling malignancy. This study was conducted …
components has shown great promise in controlling malignancy. This study was conducted …
Grape seeds: ripe for cancer chemoprevention
SK Katiyar, M Athar - Cancer Prevention Research, 2013 - AACR
A wide variety of phytochemicals, mostly flavonoids or polyphenolics, have been shown to
possess anticarcinogenic activities. Among these are the grape seed proanthocyanidins …
possess anticarcinogenic activities. Among these are the grape seed proanthocyanidins …
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