MAFbx/Atrogin-1 controls the activity of the initiation factor eIF3-f in skeletal muscle atrophy by targeting multiple C-terminal lysines
A Csibi, MP Leibovitch, K Cornille, LA Tintignac… - Journal of biological …, 2009 - ASBMB
We recently presented evidence that the subunit eIF3-f of the eukaryotic initiation translation
factor eIF3 that interacts with the E3-ligase Atrogin-1/muscle atrophy F-box (MAFbx) for …
factor eIF3 that interacts with the E3-ligase Atrogin-1/muscle atrophy F-box (MAFbx) for …
The role and regulation of MAFbx/atrogin-1 and MuRF1 in skeletal muscle atrophy
VC Foletta, LJ White, AE Larsen, B Léger… - … -European Journal of …, 2011 - Springer
Skeletal muscle atrophy occurs in many chronic diseases and disuse conditions. Its severity
reduces patient recovery, independence and quality of life. The discovery of two muscle …
reduces patient recovery, independence and quality of life. The discovery of two muscle …
Role of follistatin in muscle and bone alterations induced by gravity change in mice
N Kawao, H Morita, K Obata… - Journal of Cellular …, 2018 - Wiley Online Library
Interactions between muscle and bone have been recently noted. We reported that the
vestibular system plays crucial roles in the changes in muscle and bone induced by …
vestibular system plays crucial roles in the changes in muscle and bone induced by …
Follistatin-Related Protein and Follistatin Differentially Neutralize Endogenous vs. Exogenous Activin
Y Sidis, DV Tortoriello, WE Holmes, Y Pan… - …, 2002 - academic.oup.com
Follistatin-related protein (FSRP) is a new addition to the expanding follistatin (FS)-related
gene family whose members contain at least one conserved 10-cysteine follistatin domain …
gene family whose members contain at least one conserved 10-cysteine follistatin domain …
MAFbx/Atrogin-1 expression is a poor index of muscle proteolysis
D Attaix, VE Baracos - Current Opinion in Clinical Nutrition & …, 2010 - journals.lww.com
This issue of 'anabolic and catabolic signals' mainly contains challenging reviews on the
control of muscle mass. Two papers in this issue are devoted to recent progress in the …
control of muscle mass. Two papers in this issue are devoted to recent progress in the …
Elevated circulating follistatin associates with an increased risk of type 2 diabetes
C Wu, Y Borné, R Gao, M López Rodriguez… - Nature …, 2021 - nature.com
The hepatokine follistatin is elevated in patients with type 2 diabetes (T2D) and promotes
hyperglycemia in mice. Here we explore the relationship of plasma follistatin levels with …
hyperglycemia in mice. Here we explore the relationship of plasma follistatin levels with …
FGF-2–dependent signaling activated in aged human skeletal muscle promotes intramuscular adipogenesis
S Mathes, A Fahrner… - Proceedings of the …, 2021 - National Acad Sciences
Aged skeletal muscle is markedly affected by fatty muscle infiltration, and strategies to
reduce the occurrence of intramuscular adipocytes are urgently needed. Here, we show that …
reduce the occurrence of intramuscular adipocytes are urgently needed. Here, we show that …
Muscle sparing in muscle RING finger 1 null mice: response to synthetic glucocorticoids
Non‐Technical Summary Skeletal muscle has the capacity to modify its size in response to
external cues such as mechanical load, neural activity, hormones, stress and nutritional …
external cues such as mechanical load, neural activity, hormones, stress and nutritional …
Inactivating hepatic follistatin alleviates hyperglycemia
Unsuppressed hepatic glucose production (HGP) contributes substantially to glucose
intolerance and diabetes, which can be modeled by the genetic inactivation of hepatic …
intolerance and diabetes, which can be modeled by the genetic inactivation of hepatic …
Therapeutic approaches in facioscapulohumeral muscular dystrophy
Facioscapulohumeral muscular dystrophy (FSHD) is one of the most common types of
muscular dystrophy, affecting roughly one in 8000 individuals. The complex underlying …
muscular dystrophy, affecting roughly one in 8000 individuals. The complex underlying …