Manganese has recently been exploited for cancer immunotherapy, fenton-like reaction-
mediated chemo-dynamic therapy, and magnetic resonance imaging. The integration of …

Herein, a multi-functional nanoplatform (PDA-DTC/Cu–MnO2) was established, which has
been employed for MR imaging-guided multi-therapy (CDT, PTT and chemotherapy) for …

The limited clinical response and serious side effect have been challenging in cancer
immunotherapy resulting from immunosuppressive tumor microenvironment (TME) and …

Abstract Development of tumor microenvironment (TME) modifying nanomedicine with
cooperative effect between multiple stimuli responsive therapeutic modalities is necessary to …

The current trend of cancer therapy has changed from monotherapy to synergistic or
combination therapies. Among the treatment strategies, photodynamic therapy (PDT) and …

Currently, multimodal synergistic nanoplatform emerges as an important cancer therapy
paradigm, however, multimodal synergistic theranostic nanoplatform remains to be …

Tumor microenvironment (TME), which characteristically displays hypoxia,
immunosuppression, reprogramming metabolism and mild acidity, has been considered as …

Background Conventional chemotherapy has poor efficacy in triple-negative breast cancer
(TNBC) which is highly heterogeneous and aggressive. Imaging-guided therapy is usually …

In this study, we designed a novel peanut probe that could load oxygen molecules and
platinum (IV) prodrug (GINP-Pt) to elicit ferroptosis and apoptosis in cancer cells. In addition …

It is of great importance to develop tumor microenvironment (TME) responsive and
adjustable theranostic nano-systems for specific and efficient cancer treatment. However …