Mathematical model of heterogeneous cancer growth with an autocrine signalling pathway
GM Hu, CY Lee, YY Chen, NN Pang… - Cell proliferation, 2012 - Wiley Online Library
Objectives Cancer is a complex biological occurrence which is difficult to describe clearly
and explain its growth development. As such, novel concepts, such as of heterogeneity and …
and explain its growth development. As such, novel concepts, such as of heterogeneity and …
Relevance of microenvironmental pH for self-organized tumor growth and invasion.
M Kraus, T Severin, B Wolf - Anticancer research, 1994 - europepmc.org
The process of tumor cell growth, invasion and metastasis involves a self-organized
cascade of multiple tumor-host and tumor-immune interactions. The prediction of cancer …
cascade of multiple tumor-host and tumor-immune interactions. The prediction of cancer …
[图书][B] Scheduling of angiogenic inhibitors for Gompertzian and logistic tumor growth models
U Ledzewicz, J Munden, HM Schättler - 2009 - Citeseer
The problem of scheduling a given amount of angiogenic inhibitors is considered as an
optimal control problem with the objective of maximizing the achievable tumor reduction. For …
optimal control problem with the objective of maximizing the achievable tumor reduction. For …
Onsager's variational principle in proliferating biological tissues, in the presence of activity and anisotropy
J Ackermann, M Ben Amar - The European Physical Journal Plus, 2023 - Springer
A hallmark of biological cells is their ability to proliferate and of tissues their ability to grow.
This is common in morphogenesis and embryogenesis, but also in pathological conditions …
This is common in morphogenesis and embryogenesis, but also in pathological conditions …
Chemo-elastic modeling of invasive carcinoma development accompanied by oncogenic epithelial-mesenchymal transition
We present a further development of a multiscale chemo-mechanical model of carcinoma
growth in the epithelium tissue proposed earlier. The epithelium is represented by an elastic …
growth in the epithelium tissue proposed earlier. The epithelium is represented by an elastic …
Discrete and continuum phenotype-structured models for the evolution of cancer cell populations under chemotherapy
REA Stace, T Stiehl, MAJ Chaplain… - … Modelling of Natural …, 2020 - mmnp-journal.org
We present a stochastic individual-based model for the phenotypic evolution of cancer cell
populations under chemotherapy. In particular, we consider the case of combination cancer …
populations under chemotherapy. In particular, we consider the case of combination cancer …
Cahn–Hilliard–Brinkman model for tumor growth with possibly singular potentials
We analyze a phase field model for tumor growth consisting of a Cahn–Hilliard–Brinkman
system, ruling the evolution of the tumor mass, coupled with an advection-reaction-diffusion …
system, ruling the evolution of the tumor mass, coupled with an advection-reaction-diffusion …
[HTML][HTML] Basic ingredients for mathematical modeling of tumor growth in vitro: cooperative effects and search for space
Based on the literature data from HT-29 cell monolayers, we develop a model for its growth,
analogous to an epidemic model, mixing local and global interactions. First, we propose and …
analogous to an epidemic model, mixing local and global interactions. First, we propose and …
Viscoelastic Cahn–Hilliard models for tumor growth
We introduce a new phase field model for tumor growth where viscoelastic effects are taken
into account. The model is derived from basic thermodynamical principles and consists of a …
into account. The model is derived from basic thermodynamical principles and consists of a …
[图书][B] Mathematical Oncology 2013
A d'Onofrio, A Gandolfi, A D'Onofrio - 2014 - Springer
After a long incubation period in which only sporadic investigations were devoted to the
applications of mathematics and physics to the study of tumors (see, eg, the work of Doll and …
applications of mathematics and physics to the study of tumors (see, eg, the work of Doll and …