Genome-wide DNA methylation analysis of articular chondrocytes identifies TRAF1, CTGF, and CX3CL1 genes as hypomethylated in osteoarthritis
L Zhao, Q Wang, C Zhang, C Huang - Clinical Rheumatology, 2017 - Springer
The aim of this study is to identify osteoarthritis (OA)-associated differentially methylated
genes in human articular chondrocytes from patients with OA. DNA methylation profiling of …
genes in human articular chondrocytes from patients with OA. DNA methylation profiling of …
Genome-wide DNA methylation analysis of articular chondrocytes reveals a cluster of osteoarthritic patients
J Fernández-Tajes, A Soto-Hermida… - Annals of the …, 2014 - ard.bmj.com
Objective Alterations in DNA methylation patterns have been found to correlate with several
diseases including osteoarthritis (OA). The aim of this study was to identify, for the first time …
diseases including osteoarthritis (OA). The aim of this study was to identify, for the first time …
Increased DNA methylation and reduced expression of transcription factors in human osteoarthritis cartilage
O Alvarez‐Garcia, KM Fisch… - Arthritis & …, 2016 - Wiley Online Library
Objective To analyze the methylome of normal and osteoarthritic (OA) knee articular
cartilage and to determine the role of DNA methylation in the regulation of gene expression …
cartilage and to determine the role of DNA methylation in the regulation of gene expression …
[PDF][PDF] Characterization of the cartilage DNA methylome in knee and hip osteoarthritis
MD Rushton, LN Reynard, MJ Barter… - Arthritis & …, 2014 - Wiley Online Library
Objective The aim of this study was to characterize the genome‐wide DNA methylation
profile of chondrocytes from knee and hip cartilage obtained from patients with osteoarthritis …
profile of chondrocytes from knee and hip cartilage obtained from patients with osteoarthritis …
Genome‐wide DNA methylation study identifies significant epigenomic changes in osteoarthritic subchondral bone and similarity to overlying cartilage
MA Jeffries, M Donica, LW Baker… - Arthritis & …, 2016 - Wiley Online Library
Objective To perform a genome‐wide DNA methylation study to identify differential DNA
methylation patterns in subchondral bone underlying eroded and intact cartilage from …
methylation patterns in subchondral bone underlying eroded and intact cartilage from …
Genome‐wide DNA methylation study identifies significant epigenomic changes in osteoarthritic cartilage
MA Jeffries, M Donica, LW Baker… - Arthritis & …, 2014 - Wiley Online Library
Objective To perform a genome‐wide DNA methylation study to identify DNA methylation
changes in osteoarthritic (OA) cartilage tissue. Methods The contribution of differentially …
changes in osteoarthritic (OA) cartilage tissue. Methods The contribution of differentially …
Genome-wide DNA methylation study of hip and knee cartilage reveals embryonic organ and skeletal system morphogenesis as major pathways involved in …
E Aref-Eshghi, Y Zhang, M Liu, PE Harper… - BMC musculoskeletal …, 2015 - Springer
Background Evidence suggests that epigenetics plays a role in osteoarthrits (OA). The aim
of the study was to describethe genome wide DNA methylation changes in hip and knee OA …
of the study was to describethe genome wide DNA methylation changes in hip and knee OA …
Effect of DNA methylation on gene transcription is associated with the distribution of methylation sites across the genome in osteoarthritis
P Yi, X Xu, J Yao, B Qiu - … and Therapeutic Medicine, 2021 - spandidos-publications.com
Genetics and epigenetics are important subjects in the field of osteoarthritis (OA) research.
DNA methylation may affect gene transcription, but the specific mechanisms have remained …
DNA methylation may affect gene transcription, but the specific mechanisms have remained …
Identification of differentially methylated regions in new genes associated with knee osteoarthritis
Epigenetic changes in articular chondrocytes are associated with osteoarthritis (OA) disease
progression. Numerous studies have identified differentially methylated cytosines in OA …
progression. Numerous studies have identified differentially methylated cytosines in OA …
Analysis of mRNA expression and DNA methylation datasets according to the genomic distribution of CpG sites in osteoarthritis
P Yi, X Xu, J Yao, B Qiu - Frontiers in Genetics, 2021 - frontiersin.org
Objectives Transcriptional changes in cartilage can impact function by causing degradation
such as that which occurs during the development of osteoarthritis (OA). Epigenetic …
such as that which occurs during the development of osteoarthritis (OA). Epigenetic …