Objective The aim of this work was to characterize the genome-wide DNA methylation profile
of cartilage from three regions of tibial plateau isolated from patients with primary knee …

Objective To study epigenetic patterns in T lymphocytes that accumulate in the rheumatoid
arthritis (RA) synovium, we characterized DNA methylation of CD3+ T cells in peripheral …

Objective To determine genome‐wide methylation profiles of bone from patients with hip
osteoarthritis (OA) and those with osteoporotic (OP) hip fractures. Methods Trabecular bone …

Introduction: Rheumatoid arthritis (RA) is an autoimmune disease that causes chronic
inflammation of the joints. Recent evidence indicated the epigenetic changes may contribute …

Rheumatoid arthritis (RA) is a chronic, systemic inflammatory disease of unknown origin,
which exhibits a complex heterogeneity in its pathophysiological background, resulting in …

Osteoarthritis is one of the most prevalent chronic joint diseases for middle-aged and elderly
people. But in recent years, the number of young people suffering from the disease …

Background Knee osteoarthritis (KOA) is a degenerative knee disease commonly found in
the ageing population. DNA methylation works with histone acetylation to participate in …

Osteoarthritis (OA) is a prevalent disease of articular joints and primarily characterized by
degradation and calcification of articular cartilage. Presently, no effective treatment other …

Background: Primary Osteoarthritis (OA) is a multifactorial disease in which genetic factors
are strongly associated with its development; however, recently it has been observed that …

Objective To examine the genome‐wide distribution of hydroxymethylated cytosine (5hmC)
in osteoarthritic (OA) and normal chondrocytes in order to investigate the effect on OA …