The application of dexamethasone releasing poly (lactic-co-glycolic acid)(PLGA)
microspheres embedded in a poly vinyl alcohol (PVA) hydrogel coatings have been …

The foreign body reaction is the major cause of the dysfunction and relatively short lifetime
associated with implanted glucose biosensors. An effective strategy to maintain sensor …

Background: Hydrogels alone and in combination with microsphere drug delivery systems
are being considered as biocompatible coatings for implantable glucose biosensors to …

Dexamethasone loaded PLGA microsphere/PVA hydrogel composites were investigated as
an outer drug-eluting coating for implantable devices to provide protection against the …

Application of implantable glucose biosensors for “real-time” monitoring is reliant on
controlling the negative tissue reaction at the sensor tissue interphase. A novel polymer …

Purpose To develop and characterize microspheres using poly (lactic-co-glycolic
acid)(PLGA) blends (PLGA5050 (25 KD) and PLGA6535 (70 KD)) for dexamethasone …

A major obstacle to the development of implantable biosensors is the foreign body response
(FBR) that results from tissue trauma during implantation and the continuous presence of the …

Dexamethasone loaded poly (lactic-co-glycolic acid)(PLGA) microsphere/PVA hydrogel
composites have been investigated as an outer drug-eluting coating for implantable devices …

Background: Continuous release of dexamethasone from PLGA microsphere/PVA hydrogel
composites has been shown to suppress the inflammatory tissue reaction in response to …

Background: Successful performance of implantable glucose biosensors for metabolic
monitoring is dependent on tissue compatibility. Negative immunostimulatory tissue …