Abstract Purpose: Placental growth factor (PlGF) is an angiogenic protein. Upregulation of
PlGF has been observed in the clinic following antiangiogenic regimens targeting the VEGF …

The role of placental growth factor (PlGF) in modulation of tumor angiogenesis and tumor
growth remains an enigma. Furthermore, anti-PlGF therapy in tumor angiogenesis and …

Cells in human tumor xenografts express similar levels of angiogenic growth factors before
treatment. After radioimmunotherapy (RAIT) surviving tumor cells upregulate angiogenic …

The vascular endothelial growth factor (VEGF)-related factor, placental growth factor (PlGF),
has been shown recently to play an important role in pathological VEGF-driven …

Placental growth factor (PlGF), a homolog of vascular endothelial growth factor (VEGF),
exerts pleiotropic functions in cancer by affecting tumor cells as well as endothelial and …

Angiogenesis is one of the crucial events for cancer development and growth. Two members
of the vascular endothelial growth factor (VEGF) family, VEGF-A and placental growth factor …

Background/Aim: Placental growth factor (PlGF) is up-regulated in major malignant diseases
or following antiangiogenic therapy, although it is present in low levels under normal …

Tumor growth and metastasis require concomitant growth of new blood vessels, which are
stimulated by angiogenic factors, including vascular endothelial growth factor (VEGF) …

Introduction: There is clinical evidence that therapies targeting the vascular endothelial
growth factor pathway are effective in delaying cancer progression. However, tumors may be …

Choriocarcinomas are a rare form of cancer that develops in the uterus from tissue which
would normally become the placenta. Choriocarcinomas are a trophoblastic gestational …