Evolution of acute infections and the invasion-persistence trade-off
We seek to understand the conditions favoring the evolution of acute, highly transmissible
infections. Most work on the life-history evolution of pathogens has focused on the …
infections. Most work on the life-history evolution of pathogens has focused on the …
Pathogen evolution in finite populations: slow and steady spreads the best
The theory of life-history evolution provides a powerful framework to understand the
evolutionary dynamics of pathogens. It assumes, however, that host populations are large …
evolutionary dynamics of pathogens. It assumes, however, that host populations are large …
Host population structure and the evolution of virulence: a “law of diminishing returns”
Abstract Structure in a population of host individuals, whether spatial or temporal, can have
important effects on the transmission and evolutionary dynamics of its pathogens. One of …
important effects on the transmission and evolutionary dynamics of its pathogens. One of …
Evolution of virulence in heterogeneous host communities under multiple trade-offs
Many pathogens and parasites are transmitted through hosts that differ in species, sex,
genotype, or immune status. In addition, virulence (here defined as disease-induced …
genotype, or immune status. In addition, virulence (here defined as disease-induced …
Crossing the scale from within-host infection dynamics to between-host transmission fitness: a discussion of current assumptions and knowledge
The progression of an infection within a host determines the ability of a pathogen to transmit
to new hosts and to maintain itself in the population. While the general connection between …
to new hosts and to maintain itself in the population. While the general connection between …
Evolutionary emergence of infectious diseases in heterogeneous host populations
The emergence and re-emergence of pathogens remains a major public health concern.
Unfortunately, when and where pathogens will (re-) emerge is notoriously difficult to predict …
Unfortunately, when and where pathogens will (re-) emerge is notoriously difficult to predict …
[PDF][PDF] Within-host pathogen dynamics: Some ecological and evolutionary consequences of transients, dispersal mode, and within-host spatial heterogeneity
RD Holt, M Barfield - Disease evolution: models, concepts, and …, 2006 - people.clas.ufl.edu
The ecology and evolution of infectious disease occur at multiple spatial scales. In this
paper, we explore some consequences of transient dynamics of pathogens within individual …
paper, we explore some consequences of transient dynamics of pathogens within individual …
Death is overrated: the potential role of detection in driving virulence evolution
DA Kennedy - Proceedings of the Royal Society B, 2023 - royalsocietypublishing.org
A common assumption in the evolution of virulence theory literature is that pathogens
transmit better when they exploit their host more heavily, but by doing so, they impose a …
transmit better when they exploit their host more heavily, but by doing so, they impose a …
What limits the evolutionary emergence of pathogens?
S Gandon, ME Hochberg… - … transactions of the …, 2013 - royalsocietypublishing.org
The ability of a pathogen to cause an epidemic when introduced in a new host population
often relies on its ability to adapt to this new environment. Here, we give a brief overview of …
often relies on its ability to adapt to this new environment. Here, we give a brief overview of …
The impact of host longevity on disease transmission: host–pathogen dynamics and the evolution of resistance
U Carlsson-Granér, PH Thrall - Evolutionary Ecology …, 2006 - evolutionary-ecology.com
The impact of host longevity on disease transmission: host–pathogen dynamics and the
evolution of resistance Page 1 The impact of host longevity on disease transmission: host–pathogen …
evolution of resistance Page 1 The impact of host longevity on disease transmission: host–pathogen …