Circulating tumor cells (CTC) detection: clinical impact and future directions

P Paterlini-Brechot, NL Benali - Cancer letters, 2007 - Elsevier
Recent molecular and clinical studies have shown that invasion may occur very early in
tumor development, thus emphasizing the potential importance of specific and sensitive …

Circulating tumor cells: advances in detection methods, biological issues, and clinical relevance

YF Sun, XR Yang, J Zhou, SJ Qiu, J Fan… - Journal of cancer research …, 2011 - Springer
Abstract Background Circulating tumor cells (CTCs) have long been considered a reflection
of tumor aggressiveness. Hematogenous spreading of CTCs from a primary tumor is a …

Circulating tumour cell detection on its way to routine diagnostic implementation?

S Sleijfer, JW Gratama, AM Sieuwerts, J Kraan… - European Journal of …, 2007 - Elsevier
Circulating tumour cells (CTCs) have been considered for a long time in reflecting the
aggressiveness of tumours. As a result, many attempts have been made to develop assays …

Circulating tumor cells as promising novel biomarkers in solid cancers

ES Lianidou, A Strati, A Markou - Critical reviews in clinical …, 2014 - Taylor & Francis
The presence of circulating tumor cells (CTCs) in peripheral blood can serve as a “liquid
biopsy” approach and has thus emerged lately as one of the hottest fields in cancer …

[HTML][HTML] Current approaches for avoiding the limitations of circulating tumor cells detection methods—implications for diagnosis and treatment of patients with solid …

A Kowalik, M Kowalewska, S Góźdź - Translational Research, 2017 - Elsevier
Eight million people die of cancer each year and 90% of deaths are caused by systemic
disease. Circulating tumor cells (CTCs) contribute to the formation of metastases and thus …

[HTML][HTML] Circulating cancer cells

D Mavroudis - Annals of oncology, 2010 - Elsevier
Circulating tumour cells (CTCs) can be detected in the blood of many patients with different
types of early or advanced cancer using antibody-based assays or molecular methods. In …

[HTML][HTML] Circulating tumor cell detection technologies and clinical utility: Challenges and opportunities

Z Habli, W AlChamaa, R Saab, H Kadara, ML Khraiche - Cancers, 2020 - mdpi.com
The potential clinical utility of circulating tumor cells (CTCs) in the diagnosis and
management of cancer has drawn a lot of attention in the past 10 years. CTCs disseminate …

Circulating tumor cell analysis: technical and statistical considerations for application to the clinic

AL Allan, M Keeney - Journal of oncology, 2010 - Wiley Online Library
Solid cancers are a leading cause of death worldwide, primarily due to the failure of effective
clinical detection and treatment of metastatic disease in distant sites. There is growing …

The role of CTCs as tumor biomarkers

ES Lianidou, A Markou, A Strati - … : From biochemistry to clinic for a critical …, 2015 - Springer
Abstract Detection of Circulating Tumor Cells (CTCs) in peripheral blood can serve as a
“liquid biopsy” approach and as a source of valuable tumor markers. CTCs are rare, and …

Circulating tumour cells: their utility in cancer management and predicting outcomes

MG Krebs, JM Hou, TH Ward… - … advances in medical …, 2010 - journals.sagepub.com
Recent advances in technology now permit robust and reproducible detection of circulating
tumour cells (CTCs) from a simple blood test. Standardization in methodology has been …