Autoimmune diseases are mostly characterized by autoantibodies in the patients' serum or
cerebrospinal fluid, representing diagnostic or prognostic biomarkers. For decades …

While the T and B lymphocyte repertoires are designed to be able to recognize foreign
antigen (pathogens) to protect the host, significant portions of these repertoires can …

Autoimmune diseases, with the exception of rheumatoid arthritis and autoimmune thyroiditis,
are individually rare, but together they affect approximately 5 percent of the population in …

Rapid advances in diagnostic technologies used to detect autoantibodies have made it
difficult for even the most modern laboratory to keep abreast of the changing approaches …

This work focuses on the autoimmune processes that have now been proven to underlie a
number of serious diseases, including diabetes mellitus, rheumatoid arthritis and multiple …

The immune system specifically recognizes and eliminates foreign agents thereby protecting
the host against infection. During maturation of the immune system, immune cells that react …

Autoimmune diseases classically present with a complex etiology in which different factors
concur in the generation and maintenance of autoreactive immune responses. Some …

Autoimmune diseases are characterized by self‐reactive immune processes mediated by B
and T cells. These disorders exhibit a spectrum of clinical features that range from local or …

The genesis of this article is as a follow-up to a presentation delivered at the 2011 American
Association of Naturopathic Physicians (AANP) annual convention on the topic of …

Highlights•Metabolic programs play a key role in immune response.•Defects in metabolic
pathways associated with loss of immunological tolerance.•Systemic metabolic status …