Alterations in DNA methylation corresponding with lung inflammation and as a biomarker for disease development after MWCNT exposure
TA Brown, JW Lee, A Holian, V Porter… - …, 2016 - Taylor & Francis
Use of multi-walled carbon nanotubes (MWCNT) is growing which increases occupational
exposures to these materials. Their toxic potential makes it important to have an in-depth …
exposures to these materials. Their toxic potential makes it important to have an in-depth …
Multiwalled carbon nanotubes of varying size lead to DNA methylation changes that correspond to lung inflammation and injury in a mouse model
E Cole, JL Ray, S Bolten, RF Hamilton Jr… - Chemical Research …, 2019 - ACS Publications
Diversity in physicochemical properties of engineered multiwalled carbon nanotubes
(MWCNTs) increases the complexity involved in interpreting toxicity studies of these …
(MWCNTs) increases the complexity involved in interpreting toxicity studies of these …
[HTML][HTML] Multi-walled carbon nanotubes elicit concordant changes in DNA methylation and gene expression following long-term pulmonary exposure in mice
G Scala, MN Delaval, SP Mukherjee, A Federico… - Carbon, 2021 - Elsevier
Pulmonary exposure to multi-walled carbon nanotubes (MWCNTs) causes inflammation and
fibrosis. Our previous work has shown that industrially produced MWCNTs trigger specific …
fibrosis. Our previous work has shown that industrially produced MWCNTs trigger specific …
Changes in DNA methylation induced by multi-walled carbon nanotube exposure in the workplace
This study was designed to assess the epigenetic alterations in blood cells, induced by
occupational exposure to multi-wall carbon nanotubes (MWCNT). The study population …
occupational exposure to multi-wall carbon nanotubes (MWCNT). The study population …
DNA methylation changes in human lung epithelia cells exposed to multi-walled carbon nanotubes
Humans are increasingly exposed to nanoparticles and, although many of their
physiological effects have been described, the molecular mechanisms underlying them are …
physiological effects have been described, the molecular mechanisms underlying them are …
Differences in MWCNT-and SWCNT-induced DNA methylation alterations in association with the nuclear deposition
Background Subtle DNA methylation alterations mediated by carbon nanotubes (CNTs)
exposure might contribute to pathogenesis and disease susceptibility. It is known that both …
exposure might contribute to pathogenesis and disease susceptibility. It is known that both …
[HTML][HTML] Toxicogenomics analysis of dynamic dose-response in macrophages highlights molecular alterations relevant for multi-walled carbon nanotube-induced lung …
Toxicogenomics approaches are increasingly used to gain mechanistic insight into the
toxicity of engineered nanomaterials (ENMs). These emerging technologies have been …
toxicity of engineered nanomaterials (ENMs). These emerging technologies have been …
Changes in DNA methylation in mouse lungs after a single intra-tracheal administration of nanomaterials
AM Tabish, K Poels, HM Byun, K Luyts, AA Baccarelli… - PloS one, 2017 - journals.plos.org
Aims This study aimed to investigate the effects of nanomaterial (NM) exposure on DNA
methylation. Methods and Results Intra-tracheal administration of NM: gold nanoparticles …
methylation. Methods and Results Intra-tracheal administration of NM: gold nanoparticles …
Low-dose carbon-based nanoparticle-induced effects in A549 lung cells determined by biospectroscopy are associated with increases in genomic methylation
J Li, M Tian, L Cui, J Dwyer, NJ Fullwood, H Shen… - Scientific reports, 2016 - nature.com
Nanotechnology has introduced many manufactured carbon-based nanoparticles (CNPs)
into our environment, generating a debate into their risks and benefits. Numerous …
into our environment, generating a debate into their risks and benefits. Numerous …
[HTML][HTML] Induction and recovery of CpG site specific methylation changes in human bronchial cells after long-term exposure to carbon nanotubes and asbestos
Introduction Inhalation of asbestos induces lung cancer via different cellular mechanisms.
Together with the increased production of carbon nanotubes (CNTs) grows the concern …
Together with the increased production of carbon nanotubes (CNTs) grows the concern …
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